衢州市肺结核合并糖尿病病例特征分析

Characteristics of pulmonary tuberculosis patients complicated by diabetes mellitus in Quzhou City

目的了解衢州市肺结核合并糖尿病病例特征,为肺结核合并糖尿病防控工作提供参考。方法通过中国疾病预防控制信息系统结核病管理信息系统收集2016—2020年衢州市肺结核病例资料,描述性分析肺结核合并糖尿病病例的人口学和诊疗特征,并与单纯肺结核病例进行比较。结果2016—2020年衢州市肺结核合并糖尿病发病率为6.79/10万~9.27/10万,年递增率为8.09%。肺结核合并糖尿病病例中,男性674例,占76.94%;≥60岁620例,占70.78%;城镇居民564例,占64.38%;农民619例,占70.66%;就诊延迟537例,占61.30%;初治802例,占91.55%;病原学阳性547例,占62.44%;利福平耐药11例,占1.26%;2个月末痰涂片阴转695例,占79.34%;治疗成功783例,占89.38%。肺结核合并糖尿病病例中男性、≥60岁、城镇居民、农民、就诊延迟、病原学阳性和利福平耐药的比例高于单纯肺结核病例,2个月末痰涂片阴转的比例低于单纯肺结核病例(均P<0.05)。结论2016—2020年衢州市肺结核合并糖尿病发病率呈上升趋势,以老年男性为主,就诊延迟、病原学阳性和利福平耐药比例均高于单纯肺结核病例。

ObjectiveTo analyze the epidemiological and clinical characteristics of pulmonary tuberculosis patients complicated by diabetes mellitus(PTB-DM),so as to provide insights into PTB-DM control.MethodsThe data pertaining to PTB cases in Quzhou City from 2016 to 2020 were extracted from Tuberculosis Information Management System of Chinese Disease Prevention and Control Information System.The demographic features,diagnosis and treatment of PTBDM patients were descriptively analyzed,and compared with PTB patients.ResultsThe incidence of PTB-DM was6.79/10~5to 9.27/10~5 in Quzhou City from 2016 to 2020,with an annual increase rate of 8.09%.Among all PTB-DM patients,there were 674 men(76.94%),620 cases at ages of 60 years and older(70.78%),564 cases living in urban areas(64.38%),619 farmers(70.66%),537 cases with delay in healthcare-seeking(61.30%),802 treatment-na?ve cases(91.55%),547 cases positive for pathogenic tests(62.44%),11 cases with rifampicin resistance(1.26%),695 cases with negative conversion of sputum smears 2 months post-treatment(79.34%),and 783 cases with successful treatment(89.38%).The proportions of men,ages of 60 years and older,living in urban areas,farmers,delay in healthcare-seeking,positive pathogenic tests and rifampicin resistance were significantly higher among PTB-DM patients than among PTB patients,and the negative conversion rate of sputum smears 2 months post-treatment was significantly lower among PTB-DM patients than among PTB patients(all P<0.05).ConclusionsThe incidence of PTB-DM increased year by year in Quzhou City from 2016 to 2020,and PTB-DM cases were predominantly found among elderly men.The proportion of delay in healthcare-seeking,positive pathogenic tests and rifampicin resistance was higher among PTB-DM patients than among PTB patients.