Ⅱ型神经纤维瘤病相关听神经瘤治疗进展

Recent advance on the treatment of neurofibromatosis type 2-associated vestibular schwannoma

型神经纤维瘤病(NF2)是常染色体显性遗传性疾病,病死率和病残率较高,双侧听神经瘤在其诊断与治疗中具有重要意义,平衡治疗方法与患者生活质量是NF2相关听神经瘤治疗的关键。本文综述NF2相关听神经瘤的治疗前监测、治疗方法和听力重建进展,以为临床诊断与治疗提供参考。

Neurofibromatosis type 2(NF2)is an autosomal dominant inherited diseases.NF2 patients suffer a high mortality and disability rate.Bilateral vestibular schwannoma play an important role in its diagnosis and treatment.The balance of treatment and life quality is the key factor in the treatment of NF2-associated vestibular schwannoma.This review summarized the recent advance of monitoring before treatment,treatment strategies and hearing reconstruction in NF2-associated vestibular schwannoma,in order to provide reference for clinical diagnosis and treatment.