《重订古今名医临证金鉴·心悸怔忡卷》中心悸的用药规律分析

Analysis of medication rules of palpitation in Revisiting the Jinjian of Ancient and Modern Famous Doctors·Palpitation and Severe Palpitation Volume

目的 对《重订古今名医临证金鉴·心悸怔忡卷》中历代医家治疗心悸的用药规律进行分析。方法 通过查阅、筛选《重订古今名医临证金鉴·心悸怔忡卷》收录的历代医家治疗心悸怔忡的常用方药,进行药物频次、四气五味、归经等药性统计。采用SPSS Modeler 18.0对高频药物进行关联规则分析,IBM SPSS Statistics 20.0统计软件对高频药物进行因子分析。结果 本研究共涉及61位医家,312首古方,共有320味中药,总频次为2 995次。经统计高频药物有36味;药味以甘为主;药性以平为主;归经以心经为主;药物类别以补虚药为核心;高频药物关联规则分析得出21组常见组合。因子分析得出11组公因子。结论《重订古今名医临证金鉴·心悸怔忡卷》中治疗心悸以滋阴养血为主,常配合振奋心阳、养心安神、清热化饮祛痰等药物。

Objective To analyze the medication rules of physicians in the past dynasties in the treatment of palpitation in Revisiting the Jinjian of Ancient and Modern Famous Doctors·Palpitation and Severe Palpitation Volume.Methods Common prescriptions used by physicians of all ages for palpitation and severe palpitation,which were included in the book Revisiting the Jinjian of Ancient and Modern Famous Doctors·Palpitation and Severe Palpitation Volume were reviewed and screened.The frequency,four nature and five flavours,channel tropism of drugs,and other properties were counted.The SPSS Modeler 18.0 was used for association rule analysis of high-frequency drugs,and the statistical software IBM SPSS Statistics 20.0 was used for factor analysis of high-frequency drugs.Results A total of 61 physicians,312 ancient remedies and 320 traditional Chinese medicines were involved in this study,with a total frequency of 2 995 times.According to statistics,there were 36 kinds of high frequency drugs.The flavour of drugs was mainly sweet;the drug property was mainly flat;the main channel was the heart channel.The core of the drug category was tonifying deficiency drugs.The analysis of high-frequency drug association rules showed 21 common combinations.Factor analysis yielded 11 groups of common factors.Conclusion The treatment of palpitation in Revisiting the Jinjian of Ancient and Modern Famous Doctors·Palpitation and Severe Palpitation Volume mainly focuses on nourishing yin and nourishing blood,often combined with invigorating xinyang,nourishing the heart and calming the spirit,heat-clearing,resolving fluid retention,and dispelling phlegm,and other drugs.