中药穴位贴敷联合温热艾灸对终末期肝病患者的临床效果

Clinical effect of traditional Chinese medicine acupoint application combined with warm moxibustion on patients with end-stage liver disease

目的 探讨中药穴位贴敷联合温热艾灸对终末期肝病患者的临床效果。方法 选取2019年11月至2022年1月石家庄市第五医院(以下简称“我院”)收治的150例慢性终末期肝病患者,采用随机数字表法分为两组,各75例。对照组给予中药穴位敷贴治疗,研究组给予中药穴位贴敷联合温热艾灸治疗,连续治疗20 d。比较两组腹围、体重、24 h尿量、肝功能指标[天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、白蛋白(Alb)、总胆红素(TBil)]、终末期肝病模型(MELD)评分。结果 治疗后,两组腹围、体重低于治疗前,24 h尿量多于治疗前;且研究组腹围、体重低于对照组,24 h尿量多于对照组(P<0.05)。研究组腹围改善效果优于对照组(P<0.05)。治疗后,两组AST、ALT、TBil低于治疗前,Alb高于治疗前;且研究组AST、ALT、TBil低于对照组,Alb高于对照组(P<0.05)。治疗后10、20、30 d,两组MELD评分低于治疗前,且研究组MELD评分低于对照组(P<0.05)。结论 中药穴位贴敷联合温热艾灸能改善终末期肝病患者腹围和肝脏功能,降低MELD评分,对患者预后具有积极的影响。

Objective To investigate the clinical effect of traditional Chinese medicine acupoint application combined with warm moxibustion on patients with end-stage liver disease.Methods A total of 150 patients with chronic end-stage liver disease admitted to Shijiazhuang Fifth Hospital(hereinafter referred to as “our hospital”) from November 2019 to January2022 were selected,and they were divided into two groups by random number table method,with 75 cases in each group.The control group was given traditional Chinese medicine acupoint application therapy,and study group was given traditional Chinese medicine acupoint application combined with warm moxibustion,the treatment lasted for 20 days.The abdominal circumference,body weight,24 h urine volume,liver function indexes(aspartate aminotransferase [AST],alanine aminotransferase [ALT],albumin [Alb],total bilirubin [TBil]),and model for end-stage liver disease(MELD) score were compared.Results After treatment,the abdominal circumference and body weight of two groups were lower than those before treatment,and 24 h urine volume was more than that before treatment(P<0.05);the abdominal circumference and body weight of study group were lower than those of control group,and 24 h urine volume was more than that of control group(P<0.05).The improvement effect of abdominal circumference of study group was better than that of control group(P<0.05).After treatment,AST,ALT,and TBil of two groups were lower than those before treatment,and Alb was higher than that before treatment;and AST,ALT,and TBil of study group were lower than those of control group,and Alb was higher than that of control group(P<0.05).At 10,20,and 30 days after treatment,MELD scores in both groups were lower than those before treatment,and those in the MELD scores of study group were lower than that of control group(P<0.05).Conclusion Traditional Chinese medicine acupoint application combined with warm moxibustion can improve the abdominal circumference and liver function of patients with end-stage liver disease,reduce the MELD score,and have a positive impact on the prognosis of patients.