温针灸对脑卒中后认知功能障碍患者康复效果的Meta分析

Meta-analysis of Warming Acupuncture in the Rehabilitation of Post-Stroke Cognitive Impairment

目的系统评价温针灸治疗脑卒中后认知功能障碍患者康复效果。方法计算机检索中外数据库中使用温针灸干预脑卒中后认知功能障碍的临床随机对照试验,使用Cochrane偏倚风险评估工具对纳入文献进行方法学质量评价,采用RevMan 5.4软件对纳入指标进行Meta分析。结果最终纳入7篇文献,涉及507例脑卒中后认知功能障碍患者,Meta分析结果显示,认知功能的MoCA量表评分为[MD=2.10,95%CI(1.68,2.51),P<0.01],MMSE量表评分为[MD=2.67,95%CI(2.09,3.26),P<0.01],日常生活活动能力的BI量表评分为[MD=4.39,95%CI(2.20,6.58),P<0.01],总有效率为[OR=4.91,95%CI(1.71,14.14),P<0.01],差异均具有统计学意义。结论温针灸治疗脑卒中后认知障碍效果显著,能有效提升患者认知功能和日常生活活动能力。

Objective Meta-analysis of wanning acupuncture in the rehabilitation of post-stroke cognitive impairment.Methods The literature about the randomized controlled trials(RCTs)on the treatment of warming acupuncture in the rehabilitation of poststroke cognitive impairment were reviewed from the databases of WanFang,CNKI,VIP,CBM,PubMed,Embase,Web of Science,and Cochrane Library.Through literature screening,the quality of the finally included literature was evaluated by Cochrane bias risk assessment form,and the outcome indicators were meta analyzed by Revman 5.4 software.Results A total of 7 RCTs were included,involving 507 post-stroke cognitive impairment patients.Meta-analysis showed that,with wanning acupuncture,the score of MoCA was[MD=2.10,95%CI(1.68,2.51),P<0.01],MMSE was[MP=2.67,95%CI(2.09,3.26),P<0.01],BI was[MD=4.39,95%CI(2.20,6.58),P<0.01],the total effective rate was[OR=4.91,95%CI(1.71,14.14)],and the differences were statistically significant(P<0.05).Conclusion Warming acupuncture in the rehabilitation of post-stroke cognitive impairment have positive effect,it can effectively improve the cognitive function and activity of daily living of PSCI patients.