MRI联合经直肠超声靶向穿刺在前列腺癌中的应用

Application of MRI Combined with Transrectal Ultrasound Targeted Puncture in the Diagnosis of Prostate Cancer

本研究探讨磁共振成像(MRI)联合经直肠超声(TRUS)靶向穿刺在前列腺癌(PCA)中的应用价值。选取采用MRI联合经直肠超声靶向穿刺的234例前列腺病变患者作为靶向组,其中PCA患者114例(PCA组)、前列腺良性增生患者120例(良性组),对比两组患者的影像学特征。此外,同期采用传统12针法经直肠超声穿刺的106例前列腺病变患者作为对照组,对比两种穿刺方式的穿刺针数和穿刺获取的癌组织长度。结果显示,MRI影像学特征中,PCA组的T2WI低信号、病灶形态不规则、病灶边界模糊、弥散加权成像呈高信号患者的占比显著高于良性组患者(P<0.05)。超声影像特征比较,PCA组患者的低回声、病灶形态不规则、微钙化病灶、后方回声衰减、血流分级(2~3级)患者占比显著高于良性组患者(P<0.05)。靶向组患者的平均穿刺针数显著低于对照组(P<0.05)。靶向组患者穿刺获取的癌组织长度显著大于对照组(P<0.05)。MRI联合经直肠超声靶向穿刺诊断前列腺癌具有更高的临床价值。

This study explored the application of MRI combined with transrectal ultrasound(TRUS)targeted puncture in the diagnosis of prostate cancer(PCA).234 patients with prostate disease diagnosed by MRI combined with transrectal ultrasound targeted puncture were selected as the targeted group,including 114 patients with PCA(PCA group)and 120 patients with benign prostatic hyperplasia(benign group),and then the imaging features of the two groups were compared.In addition,106 patients in the same period with prostate disease who received traditional 12-needle transrectal ultrasound puncture were selected as the control group.Compared the number of puncture needles and the length of cancer tissue obtained by the two puncture methods.The results showed that in MRI features,the proportion of patients with low T2WI signal,irregular lesion morphology,blurred lesion boundary and diffusion-weighted imaging with high signal in PCA group was significantly higher than that in benign group(P<0.05).Comparison of ultrasound imaging features,the proportion of patients with hypoecho,irregular shape of lesions,microcalcified lesions,posterior echo attenuation,and blood flow grade(2-3)in PCA group was significantly higher than that in benign group(P<0.05).The average number of puncture needles in the targeted group was significantly lower than that in the control group(P<0.05).The length of cancer tissue obtained by puncture in the targeted group was longer than that in the control group(P<0.05).MRI combined with transrectal ultrasound targeted puncture has higher clinical value in the diagnosis of prostate cancer.