摘要
绝大多数的分化型甲状腺癌患者经过手术、131 I治疗和TSH抑制治疗后预后良好,但仍有部分患者发生区域淋巴结或远处转移,最常见的就是颈部淋巴结转移,且部分颈部淋巴结转移灶在初始或治疗过程中出现失分化现象,发展成为碘难治性甲状腺癌。碘难治性甲状腺癌严重影响患者的预后及生存率,成为临床诊治的难点和重点。本文对碘难治性甲状腺癌患者的颈部淋巴结转移灶诊断及局部治疗进展进行综述。
The vast majority of patients with differentiated thyroid carcinoma can achieve a good prognosis after surgery,radioiodine therapy,and stimulating hormone suppression therapy.However,there are still certain amount of local or distant metastasis cases,and the most common is cervical lymph node metastasis.Some cervical lymph node metastases lose the ability to concentrate radioiodine at the early stage or during radioiodine therapy,and develop radioiodine-refractory DTC(RAIR-DTC).RAIR-DTC can seriously affect patients’prognosis and survival rate and appear to be a barrier of clinical diagnosis and treatment.In this paper,the recent advances in the diagnosis and local treatment of cervical lymph node metastasis of RAIR-DTC are summarized.
作者
陆路
蒋泽文
赵守松
牟兴宇
付巍
LU Lu;JIANG Zewen;ZHAO Shousong;MOU Xingyu;FU Wei(Department of Nuclear Medicine,Affiliated Hospital of Guilin Medical University,Guilin 541001,China)
出处
《标记免疫分析与临床》
CAS
2022年第11期1967-1972,共6页
Labeled Immunoassays and Clinical Medicine
基金
桂林医学院附属医院教职工科研能力提升项目(编号:2019GLMU1A009)。
关键词
甲状腺癌
颈部淋巴结
碘难治
局部治疗
Thyroid cancer
Cervical lymph nodes metastasis
Refractory
Local treatment
