肌内注射灭多威中毒1例

A case of intramuscular injection of methomyl poisoning

灭多威是在农药中使用广泛的一种氨基甲酸酯类杀虫剂,其中毒方式多为经消化道、呼吸道和皮肤接触,目前未见经肌内注射引起中毒报道。本文分析1例肌内注射灭多威中毒患者,约4 min后出现胆碱能危象及中枢抑制,迅速给予静脉-静脉体外膜肺氧合(VV-ECMO)、阿托品等治疗,最后患者成功获救,且预后良好。肌内注射灭多威后可迅速出现胆碱能危象,起病速度明显快于消化道、呼吸道和皮肤接触途径。

Methomyl is a carbamate insecticide widely used in pesticides.Most of the poisoning methods are through digestive tract,respiratory tract and skin contact.At present,there is no report of poisoning caused by intramuscular injection.A case of poisoning caused by intramuscular injection of methomyl was analyzed retrospectively.About 4 minutes later,cholinergic crisis and central inhibition occurred.Venovenous-Extracorporeal Membrane Oxygenation(VV-ECMO)and atropine were given quickly.Finally,the patient was successfully rescued and had a good prognosis.After intramuscular injection of methomyl,cholinergic crisis can occur rapidly,and the onset rate is significantly faster than that of digestive tract,respiratory tract and skin contact.