Early detection of gastric cancer in China:progress andopportunities

In the past decade, the Chinese government has committed to promoting gastric cancer (GC) prevention and control1,2. GC is a major malignancy globally, and nearly half of GC cases and specific deaths worldwide occur in China;moreover, GC is frequently diagnosed in local advanced or advanced stages with poor prognosis3-5. GC progression is known to involve a multi-stage evolutionary cascade from precancerous gastric lesions, thus theoretically enabling the identification of high-risk populations and early detection of GC6.