基于数据挖掘的针刺治疗糖尿病足选穴规律分析

Rule of acupoint selection in acupuncture treatment of diabetic foot:An analysis based on data mining

目的:挖掘针刺治疗糖尿病足的选穴配伍规律。方法:检索中国知网(CNKI)、万方数据(WANFANG DATA)、维普中文科技期刊数据库(VIP)、PubMed、ScienceDirect等数据库自建库至2022年6月1日发表的针刺治疗糖尿病足的临床文献。建立Excel数据库,并采用开源软件R语言中的arules包和arulesViz包进行数据挖掘和可视化。结果:共获得处方75首,涉及穴位57个(含经外奇穴7个),经脉11条。针刺治疗糖尿病足使用频次排名前6位的穴位依次为足三里、三阴交、阳陵泉、阴陵泉、丰隆、太溪;使用频次排名前3位的经脉依次为足阳明胃经、足太阴脾经、足少阳胆经;穴位部位主要在下肢部和腰背部。关联规则分析显示临床选用穴位具有高度相关性,关联规则的前20项中主要为足三里、三阴交、阴陵泉、阳陵泉之间及其部分与曲池、丰隆、关元之间的联系。结论:针刺治疗糖尿病足主要取足阳明胃经、足太阴脾经、足少阳胆经的下肢部位穴位,核心穴位为足三里、三阴交、阴陵泉、阳陵泉,配伍时多采用阴阳经、表里经并取。

Objective:To investigate the rule of acupoint selection and compatibility in acupuncture treatment of diabetic foot based on data mining.Methods:Databases including CNKI,WANFANG DATA,VIP,PubMed,and ScienceDirect were searched for clinical articles on acupuncture treatment of diabetic foot published up to June 1st,2022.An Excel database was established,and the arules and arulesViz packages of open-source R language software were used for data mining and visualization.Results:A total of 75 prescriptions were obtained,involving 57 acupoints(including 7 extra ordinary points)and 11 meridians.In acupuncture treatment of diabetic foot,the top 6 acupoints in terms of frequency were Zusanli,Sanyinjiao,Yanglingquan,Yinlingquan,Fenglong,and Taixi;the top 3 meridians in terms of frequency were the stomach meridian of foot-Yangming,the spleen meridian of foot-Taiyin,and the gallbladder meridian of foot-Shaoyang;the acupoints in lower extremities and lower back were mainly selected for treatment.Association rule analysis showed a high degree of association between the acupoints selected in clinical practice,and the top 20 association rules mainly involved the association between Zusanli,Sanyinjiao,Yinlingquan,and Yanglingquan,as well as their association with Quchi,Fenglong,and Guanyuan.Conclusion:In acupuncture treatment of diabetic foot,the acupoints of the stomach meridian of foot-Yangming,the spleen meridian of foot-Taiyin,and the gallbladder meridian of foot-Shaoyang located in lower extremities are mainly selected for treatment,and the core acupoints are Zusanli,Sanyinjiao,Yinlingquan,and Yanglingquan.The acupoints in both Yin-Yang meridians and exterior-interior meridians are selected for combination.