超声造影经直肠前列腺靶向穿刺活检术在PSA 4~10 ng/ml患者中的作用

Effect of contrast-enhanced ultrasound transrectal targeted prostate biopsy in patients with PSA4-10 ng/ml

目的探讨超声造影经直肠前列腺靶向穿刺活检术(CETRUS-PB)在PSA 4~10 ng/ml患者中的作用。方法2016年1月至2018年12月,番禺中心医院82例泌尿外科收治的PSA 4~10 ng/ml的患者根据自愿原则被分入系统性经直肠超声前列腺穿刺活检术组(STRUS-PB)和CETRUS-PB组,比较两组穿刺的效率、视觉模拟疼痛评分(VAS)以及并发症。结果CETRUS-PB与STRUS-PB组在PSA 4~10 ng/ml的患者中穿刺阳性率差异无统计学意义(P=0.147),两组穿刺针数、Gleason评分以及视觉疼痛评分的比较差异有统计学意义(P<0.001),两组均未出现严重并发症。结论在PSA 4~10 ng/ml患者中,CETRUS-PB不能显著提高穿刺阳性率,但可以提高穿刺的精准度,减少穿刺针数,减轻痛苦。

Objective To investigate the role of contrast-enhanced ultrasound transrectal targeted prostate biopsy(CETRUS-PB)in patients with PSA 4-10 ng/ml.Methods 82 patients with PSA 4-10 ng/ml were divided into two groups on a voluntary basis:systematic transrectal ultrasound prostate biopsy(STRUS-PB)group and CETRUS-PB group from January 2016 to December 2018 in Central Hospital of Panyu District.The biopsy efficiency,VAS and complications were compared between the two groups.Results The positive rate of STRUS-PB group and CETRUS-PB group in PSA 4-10 ng/ml patients had no significant difference(P=0.147).There was significant difference in the number of biopsy needles,Gleason score and VAS between the two groups(P<0.001).There was no serious complications in both groups.Conclusions In patients with PSA 4-10 ng/ml,CETRUS-PB can not significantly improve the positive rate of prostate biopsy compared with STRUS-PB,but it may improve the accuracy of biopsy,reduce the number of biopsy needles and reduce pain.