摘要
探讨帕瑞昔布钠联合银杏达莫注射液用于治疗脓毒症的效果。研究发现与治疗前相比,治疗后7 d两组患者CRP、PCT、IL-6水平均显著下降,且治疗组较对照组各指标水平下降更明显( P<0.05),治疗组的28 d生存率显著高于对照组。帕瑞昔布钠联合银杏达莫注射液治疗脓毒症患者可减轻机体炎症反应,调整其微循环和肾功能状态。
The purpose of this study was to investigate the therapeutic efficacy of Parecoxib sodium plus Ginkgo leaf extract and Dipyridamole injection in the treatment of sepsis.The study found that,compared with baseline,the levels of CRP,PCT,and IL-6 in the treatment group and the control group were significantly lowered at 7 days after treatment,and the reduction in these indicators was more significant in the treatment group than that in the control group(P<0.05).The survival rate was significantly higher in the treatment group than that in the control group.In summary,Parecoxib sodium plus Ginkgo leaf extract and Dipyridamole injection as a treatment of sepsis can ameliorate inflammatory response,improve microcirculation and renal function in the patients.
作者
夏天
李金秀
薛秀岳
刘清岳
Xia Tian;Li Jinxiu;Xue Xiuyue;Liu Qingyue(Department of Pharmacy,Liaocheng Second People’s Hospital,Second Liaocheng Hospital Affiliated to Shandong First Medical University,Liaocheng 252600,Shandong,China;Department of Critical Care Medicine,Liaocheng Second People’s Hospital,Second Liaocheng Hospital Affiliated to Shandong First Medical University,Liaocheng 252600,Shandong,China)
出处
《中华生物医学工程杂志》
CAS
2022年第5期578-581,共4页
Chinese Journal of Biomedical Engineering
基金
山东省医药卫生科技发展计划项目(202010001261)。
关键词
银杏达莫注射液
帕瑞昔布钠
脓毒症
炎症
微循环
免疫功能
Ginkgo leaf extract and Dipyridamole injection
Parecoxib sodium
Sepsis
Inflammation
Microcirculation
Immunity
