山东省滕州市HIV/AIDS抗病毒治疗及时性及影响因素分析

Analysis on timeliness and influencing factors of antiviral therapy for AIDS patients,Tengzhou city,Shandong province

目的分析山东省滕州市2017-2021年新报告HIV感染者/AIDS患者(以下简称HIV/AIDS)接受抗病毒治疗的及时性及影响因素,为提高HIV/AIDS抗病毒治疗效果提供参考。方法通过艾滋病综合防治基本信息系统,收集2017-2021年山东省滕州市新报告的HIV/AIDS相关信息,使用χ^(2)趋势检验分析抗病毒治疗及时率时间变化趋势,采用二分类logistic回归模型分析抗病毒治疗及时率的影响因素。结果2017-2021年滕州市新报告HIV/AIDS 131例,均为汉族,以男性(87.0%)、同性传播(72.5%)为主,5年抗病毒治疗及时率分别为42.9%、68.8%、50.0%、71.4%、84.0%,呈增长趋势(χ^(2)趋势=11.8,P<0.05);已婚或有配偶(O R=4.10,95%CI:1.10~15.46)、2021年新报告HIV/AIDS抗病毒治疗及时率较高(O R=8.28,95%CI:1.54~44.48);年龄45~54岁者抗病毒治疗及时率较低(O R=0.11,95%CI:0.02~0.79)。结果2017-2021年山东省滕州市HIV/AIDS抗病毒治疗及时率呈逐年增高趋势,单身及45~54岁HIV/AIDS者抗病毒治疗及时率较低。

Objective To analyze the timeliness and influencing factors of newly reported HIV infected/AIDS patients(hereafter referred to as HIV/AIDS)receiving antiviral therapy from 2017 to 2021 in Tengzhou city,Shandong province,so as to provide reference for improving the efficacy of antiviral therapy for AIDS patients.Methods The information of HIV/AIDS patients newly reported in Tengzhou city,Shandong province from 2017 to 2021 was collected through the Basic Information System of HIV/AIDS Comprehensive Prevention and Treatment.The time variation trend of antiviral treatment timeliness rate was analyzed by Chi-square trend test,and the influencing factors of antiviral treatment timeliness rate were analyzed by binary logistic regression model.Results There were 131 newly reported HIV/AIDS patients in Tengzhou city from 2017 to 2021,all of whom were Han nationality,mainly male(87.0%)and homosexual transmission(72.5%).The 5-year timely rate of antiviral treatment was 42.9%,68.8%,50.0%,71.4%and 84.0%,respectively,showing an increasing trend(χ^(2)=11.8,P<0.05);Patients who were married or had permanent spouse(O R=4.10,95%CI:1.10-15.46),newly reported in 2021(O R=8.28,95%CI:1.54-44.48)had a high rate of timely antiviral treatment;The timely rate of antiviral treatment was lower in those aged 45-54 years(O R=0.11,95%CI:0.02-0.79).Conclusion The timely rate of antiviral treatment in HIV/AIDS patients showed an increasing trend from 2017 to 2021 in Tengzhou city,Shandong province.The rate of patients got timely antiviral treatment in single and 45-54 year old patients was low.