200例儿童呼吸道感染临床及实验室特征

Clinical and laboratory characteristics of 200 children with respiratory tract infection

目的探讨200例儿童呼吸道感染临床及实验室特征。方法对2017年1月-2020年9月海南省三亚市人民医院儿科收治的200例呼吸道感染患儿的临床资料做回顾性分析。按致病病原体不同将全部患儿分成三组,分别为病毒感染组83例、细菌感染组65例、肺炎支原体感染组52例。比较三组患儿的一般资料(性别、年龄、病程、咳嗽、咳痰、肺部罗音等)、血常规[白细胞计数(WBC)]、肺炎支原体IgM抗体(MP-IgM)、C-反应蛋白(CRP)、血清降钙素原(PCT)检测阳性率。结果三组患儿一般资料比较,无统计学差异。细菌感染组WBC、CRP、PCT均高于其他两组(P<0.05);细菌感染组CRP阳性率、PCT阳性率高于其他两组(P<0.05),肺炎支原体感染组的MP-IgM阳性率高于其他两组(P<0.05)。结论临床上可以通过联合监测WBC、CRP、PCT、肺炎支原体抗体水平对儿童呼吸道医院感染进行诊断与鉴别诊断。

OBJECTIVE To explore the clinical and laboratory characteristics of 200 children with respiratory tract infection.METHODS The clinical data that were collected from 200 children with respiratory tract infection who were treated in Sanya People’s Hospital from Jan 2017 to Sep 2020 were retrospectively analyzed.All of the children were divided into the viral infection group with 83 cases,the bacterial infection group with 65 cases and the Mycoplasma pneumoniae infection group with 52 cases according to the pathogens.The baseline data(gender,age,course of disease,cough,expectoration,pulmonary rales),blood routine[white blood cell(WBC)]and positive rates of M.pneumoniae IgM antibody(MP-IgM),C-reactive protein(CRP)and serum procalcitonin(PCT)were observed and compared among the three groups of children.RESULTS There was no significant difference in the baseline data among the three groups of patients.The levels of WBC,CRP and PCT of the bacterial infection group were higher than those of other two groups(P<0.05).The positive rates of CRP and PCT of the bacterial infection group were higher than those of other two groups(P<0.05),while the positive rate of MP-IgM of the M.pneumoniae infection group was higher than that of other two groups(P<0.05).CONCLUSION The joint detection of WBC,CRP,PCT and M.pneumoniae antibody may facilitate the diagnosis and differential diagnosis of respiratory tract infection in the children.