延时成像监测技术在体外受精-胚胎移植中的应用研究进展

Research progress in the application of time-lapse imaging monitoring technology in in vitro fertilization-embryo transfer

体外受精-胚胎移植周期中减少多胎妊娠最有效的方法是选择性单胚胎移植,而评估胚胎的发育潜能是关键的步骤之一。目前评估胚胎发育潜能大部分采用静态评估系统,通过胚胎的形态学进行评估,具有一定的主观性和局限性。随着延时成像监测技术的广泛应用,可通过形态动力学参数和胚胎的分裂模式进行综合评估,既能提供评估胚胎发育潜能的更多有价值参数,还可以克服静态评估的局限性。该文将对延时成像监测技术在体外受精-胚胎移植中的应用研究进展作一综述。

The most effective method to reduce multiple pregnancies in in vitro fertilization-embryo transfer(IVF-ET)cycles is selective single embryo transfer,and assessing the developmental potential of embryos is one of the key steps.Currently,static assessment systems are mostly used to assess the developmental potential of embryos,which are based on the morphology of the embryos and have certain subjectivity and limitations.With the widespread use of time-lapse imaging monitoring technology(time-lapse),a comprehensive assessment can be performed by morphokinetic parameters and embryo cleavage patterns,which not only provides more valuable parameters for assessing the developmental potential of embryos,but also overcomes the limitations of static assessment.This paper reviews the research progress in the application of time-lapse in IVF-ET.