中医综合疗法治疗单纯性肥胖痰湿证的疗效及对患者内脏脂肪面积的影响

Effect of Comprehensive Therapy of Traditional Chinese Medicine on Visceral Fat Area in Simple Obesity Patients with Phlegm-Dampness Syndrome

目的:观察中医综合疗法治疗单纯性肥胖痰湿证的疗效及对患者内脏脂肪面积的影响。方法:收集2017年10月至2020年3月在广东省中医院内分泌科门诊就诊的406例辨证为痰湿证的单纯性肥胖患者,采用前瞻性、随机对照研究,按随机数字表法分为两组,最终完成试验362例,其中对照组患者183例,采用单纯生活方式管理;干预组患者179例,采用清脂茶、清脂饼、腹部按摩操三联中医综合干预,治疗12周。观察体质量指数(BMI)、体质量、腰围、臀围、血脂、体脂肪、体脂率、内脏脂肪面积的变化,并评价疗效。结果:干预组总有效率高于对照组,差异有统计学意义(P<0.05)。干预后,对照组患者体质量、BMI、腰围、臀围、血脂、体脂肪、体脂率与干预前比较,差异均无统计学意义(P>0.05);干预后,干预组患者胆固醇、低密度脂蛋白与干预前比较,差异均无统计学意义(P>0.05)。干预后,干预组患者体质量、BMI、腰围、臀围、甘油三酯、体脂肪、内脏脂肪面积较干预前下降,差异均有统计学意义(P<0.05)。干预后,干预组患者体脂肪、内脏脂肪面积、体脂率均低于对照组,差异均有统计学意义(P<0.05)。结论:中医综合疗法可有效地减轻单纯性肥胖痰湿证患者体质量,降低甘油三酯,减少体脂肪及内脏脂肪面积,临床疗效显著。

Objective:To observe the effectiveness of comprehensive therapy of traditional Chinese medicine on simple obesity with phlegm-dampness syndrome and its effect on visceral fat area.Methods:This study used a prospective,randomized controlled method to enroll 406 patients with simple obesity that were diagnosed with phlegm-dampness syndrome in the Department of Endocrinology of Guangdong Hospital of Traditional Chinese Medicine from October 2017 to Match 2020.The patients were divided into two groups according to the random number table method.Totally 362 patients finally completed the test.Among them,183 cases in the control group used pure lifestyle intervention,and the 179 cases in the intervention group were given three methods of Qingzhi tea(清脂茶),Qingzhi biscuits(清脂饼)and abdominal massage based on lifestyle intervention.Both groups intervened for 12 weeks.The changes of body mass index(BMI),body weight,waist circumference,hip circumference,blood lipid,body fat,body fat rate and visceral fat area were observed before and after treatment.Results:The intervention group showed higher total efficiency than control group,with statistically significant difference(P<0.05).After the intervention,there was no significant difference in weight,BMI,waist circumference,hip circumference,blood lipid,body fat and body fat rate between before and after intervention in control group(P>0.05).There was no significant difference in cholesterol and low density lipoprotein between before and after intervention in intervention group(P>0.05).After the intervention,the weight,BMI,waist circumference,hip circumference,triglyceride,body fat and visceral fat area decreased in the intervention group,and the difference was statistically significant(P<0.05).After the intervention,the intervention group showed lower body fat,visceral fat area and body fat rate than control group,and the difference was statistically significant(P<0.05).Conclusion:Comprehensive treatment of traditional Chinese medicine can safely and effectively reduce body weight,triglyceride,body fat and visceral fat area,and the clinical effect is significant.