JAK-STAT信号通路与玫瑰痤疮

JAK-STAT signaling pathway and rosacea

研究表明玫瑰痤疮与炎症因子、神经脉管功能、微生态环境等多种因素有关。JAK-STAT信号通路涉及多种炎症细胞因子,在细胞增殖、分化、凋亡和血管生成及免疫调节等方面发挥重要作用。本文将概述JAK-STAT信号通路并探讨其在玫瑰痤疮中的潜在作用。

Studies have shown that rosacea is related to inflammatory factors,neurovascular function,micro-ecological environment and other factors.The Janus kinase(JAK)-signal transducer and activator of transcription(STAT)signaling pathway involves a variety of inflammatory cytokines,and plays an important role in cell proliferation,differentiation,apoptosis,angiogenesis and immune regulation.This review summarizes the JAK-STAT signaling pathway and explores its potential role in rosacea.