肠道菌群与黑素瘤免疫检查点抑制剂治疗的研究进展

Gut microbiota and immune checkpoint inhibitor treatment of melanoma

越来越多的研究表明,肠道菌群通过多种机制影响黑素瘤的发展,且在黑素瘤治疗过程中扮演重要的角色。本文就肠道菌群与黑素瘤发展的关系,肠道菌群对黑素瘤免疫检查点抑制剂治疗及相关不良反应的影响作一综述。

A growing number of studies have shown that gut microbiota affects the development of melanoma through various mechanisms,and plays a vital role in the treatment of melanoma.This review summarizes the relationship between gut microbiota and the development of melanoma,the effect of gut microbiota on the checkpoint blockade immunotherapy of melanoma and related adverse effects.