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益气化瘀利水汤辅助地奥司明与氢氯噻嗪治疗乳腺癌术后上肢淋巴水肿临床研究 被引量:2

Clinical Study on Yiqi Huayu Lishui Tang Assisting Diosmine and Hydrochlorothiazide for Upper Limb Lymphedema After Breast Cancer Surgery
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摘要 目的:观察益气化瘀利水汤辅助地奥司明与氢氯噻嗪治疗乳腺癌术后上肢淋巴水肿的临床疗效。方法:回顾性选取50例乳腺癌术后上肢淋巴水肿患者的临床资料,根据治疗方法不同分为研究组和对照组各25例。对照组给予地奥司明和氢氯噻嗪治疗,研究组在对照组基础上给予益气化瘀利水汤治疗。评价2组临床疗效,比较2组淋巴水肿自感症状、上肢功能、上臂臂围差值及疼痛程度。结果:研究组临床总缓解率优于对照组(P<0.05)。治疗前,2组淋巴水肿与乳腺癌问卷(LBCQ)评分、上肢功能评分量表(DASH)评分比较,差异无统计学意义(P>0.05)。治疗后,2组LBCQ评分、DASH评分低于治疗前(P<0.05);研究组LBCQ评分、DASH评分低于对照组(P<0.05)。治疗前,2组上臂臂围差值比较,差异无统计学意义(P>0.05)。治疗2周、4周,2组上臂臂围差值较治疗前呈下降趋势(P<0.05),且研究组上臂臂围差值低于同时间点对照组(P<0.05)。治疗前,2组疼痛视觉模拟量表(VAS)评分比较,差异无统计学意义(P>0.05)。治疗2周、4周,2组VAS评分较治疗前呈下降趋势(P<0.05),且研究组VAS评分低于同时间点对照组(P<0.05)。结论:益气化瘀利水汤辅助地奥司明、氢氯噻嗪有利于提高乳腺癌术后上肢淋巴水肿患者临床疗效,改善临床症状,减轻水肿和疼痛,提高上肢功能。 Objective:To observe the clinical effect of Yiqi Huayu Lishui Tang assisting Diosmine and Hydrochlorothiazide for upper limb lymphedema after breast cancer surgery.Methods:The clinical data of50 patients with upper limb lymphedema after breast cancer surgery were retrospectively selected.According to their different treatment methods,the patients were divided into the study group and the control group,with 25 cases in each group.The control group was treated with Diosmin and Hydrochlorothiazide,and the study group was additionally treated with Yiqi Huayu Lishui Tang on the basis of the treatment of the control group.The clinical effects in the two groups were evaluated,and the selfperceived symptoms of lymphedema,upper limb function,the difference in upper arm circumference and pain degree in the two groups were compared.Results:The total clinical remission rate in the study group was better than that in the control group(P0.05).After treatment,the scores of LBCQ and DASH in the two groups were lower than those before treatment(P0.05).After treatment for two and four weeks,the difference in upper arm circumference in the two groups showed a downward trend when compared with that before treatment(P0.05).After treatment for two and four weeks,VAS scores in the two groups showed a downward trend when compared with that before treatment(P<0.05),and the VAS score in the study group was lower than that in the control group at the same time point(P<0.05).Conclusion:Yiqi Huayu Lishui Tang combined with Diosmin and Hydrochlorothiazide can improve the clinical effect of upper limb lymphedema after breast cancer surgery,improve the clinical symptoms and the function of upper limb,and relieve edema and pain.
作者 侯立玲 郭伟 田廷斌 HOU Liling;GUO Wei;TIAN Tingbin
机构地区 德州联合医院
出处 《新中医》 CAS 2022年第23期149-153,共5页 New Chinese Medicine
关键词 乳腺癌 上肢淋巴水肿 益气化瘀利水汤 地奥司明 氢氯噻嗪 淋巴水肿与乳腺癌问卷 上肢功能 视觉模拟评分 Breast cancer Lymphedema of upper limb Yiqi Huayu Lishui Tang Diosmin Hydrochlorothiazide Lymphedema and Breast Cancer Questionnaire Upper limb function Visual Analogue Scale
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