葛根素注射液对后半规管良性阵发性位置性眩晕患者DHI评分的影响

Effect of Puerarin Injection on DHI Score in Patients with Benign Paroxysmal Positional Vertigo of Posterior Semicircular Canal

目的:观察葛根素注射液联合Epley手法复位治疗后半规管良性阵发性位置性眩晕(PC-BPPV)的临床疗效,并分析其对PC-BPPV患者眩晕残障程度评定量表(DHI)评分的影响。方法:采用随机数字表法将80例PC-BPPV患者随机分为对照组与研究组各40例。对照组采用Epley手法复位治疗,研究组在此基础上联合葛根素注射液治疗,2组均连续治疗2周。比较2组临床疗效及治疗前后中医证候积分、DHI评分,并随访6个月,比较2组PC-BPPV复发情况。结果:研究组治疗总有效率92.50%,高于对照组72.50%(P<0.05)。治疗前,2组中医证候积分比较,差异无统计学意义(P>0.05);治疗1周、2周后,2组中医证候积分逐渐降低(P<0.05),且研究组低于对照组(P<0.05)。治疗前,2组DHI评分比较,差异无统计学意义(P>0.05);治疗1周、2周后,2组DHI评分逐渐降低(P<0.05),且研究组低于对照组(P<0.05)。治疗后6个月内,研究组复发率2.50%,低于对照组17.50%(P<0.05)。结论:葛根素注射液联合Epley手法复位治疗PC-BPPV疗效显著,可有效改善PC-BPPV患者疾病症状,降低疾病复发率,可作为临床治疗PC-BPPV的一种有效辅助手段。

Objective:To observe the clinical effect of the therapy of Puergin Injection combined with Epley manipulation on patients with benign paroxysmal positional vertigo of posterior semicircular canal(PCBPPV),and to analyze its effect on scores of Dizziness Handicap Inventory(DHI).Methods:A total of80 PC-BPPV patients were divided into the control group and the study group according to the random number table method,with 40 cases in each group.The control group was treated with Epley manipulation,and the study group was additionally treated with Puerarin Injection on this basis.Both groups were treated for two weeks.The clinical effects,Chinese medicine syndrome scores and DHI scores before and after treatment were compared between the two groups,and the two groups were followed up for six months,and the recurrence of PC-BPPV was compared.Results:The total effective rate was 92.50% in the study group,higher than that of 72.50% in the control group(P0.05).After one week and two weeks of treatment,the Chinese medicine syndrome scores in the two groups were gradually decreased(P0.05).After one week and two weeks of treatment,the DHI scores in the two groups were gradually decreased(P<0.05),and the score in the study group was lower than that in the control group(P<0.05).Within six months after treatment,the recurrence rate was 2.50% in the study group,lower than that of 17.50% in the control group(P<0.05).Conclusion:The therapy of Puerarin Injection combined with Epley manipulation has a significant therapeutic effect on the treatment of PC-BPPV,which can effectively improve the disease symptoms and reduce the recurrence rate of the disease,and it can be used as an effective auxiliary method for clinical treatment of PC-BPPV.