抗呼吸道病毒单克隆抗体药物的研发进展及应用

Development progress and application of monoclonal antibody drugs against respiratory virus

近年来,呼吸道传染病在全球范围内暴发和流行,严重危害人类健康,其中因病毒感染导致的呼吸道传染病占很大比例。疫苗和常用抗病毒药物的使用是对抗病毒感染的有效途径,但也存在滞后性和耐药性等问题,针对呼吸道病毒性传染病的单克隆抗体为其临床治疗提供了新的策略。本文对抗呼吸道病毒单克隆抗体药物的研发进展及其在呼吸道病毒性传染病中的应用作一综述。

In recent years,the outbreak and prevalence of respiratory infectious diseases in the world seriously endanger human health,among which the respiratory infectious diseases caused by viral infection account for a large proportion.The use of vaccines and common antiviral drugs is an effective way to fight viral infection,but there are also problems such as lag and drug resistance.Monoclonal antibodies against respiratory viral infections provide a new strategy for clinical treatment.This paper reviews the development of monoclonal antibody against respiratory virus and its application in respiratory viral infectious diseases.