止嗽散合三子养亲汤加减对老年肺炎的临床效果

Clinical effect of Zhisou powder combined with Sanzi Yangqin decoction on senile pneumonia

目的 探讨止嗽散合三子养亲汤加减对老年肺炎的总疗效及症状缓解、肺功能改善价值。方法 选取2018年1月—2021年2月本院收治的老年肺炎患者150例,按随机数字表法分为实验组(n=75)与对照组(n=75),对照组采用常规西药,实验组在对照组基础上加用止嗽散合三子养亲汤加减治疗。对比2组临床疗效、症状缓解时间、治疗前后肺功能[第1 s用力呼气容积(FEV1)、用力肺活量(FVC)]。组间比较采用t检验、χ^(2)检验。结果 实验组治疗总有效率为94.67%,高于对照组的80.00%(χ^(2)=7.292,P=0.007);实验组咳痰咳嗽消失时间、炎症吸收时间、肺部啰音消失时间分别为(5.12±0.42)d、(8.10±0.58)d、(8.68±0.53)d,均短于对照组的(7.15±0.65)d、(11.02±0.89)d、(6.98±0.46)d(t=22.717、23.805、20.979,P<0.01);治疗后,实验组FEV1、FVC分别为(2.87±0.18)L、(4.02±0.25)L,均大于对照组的(1.76±0.14)L、(2.65±0.21)L(t=42.155、36.339,P<0.01)。结论 止嗽散合三子养亲汤加减治疗老年肺炎,可提高临床疗效,改善临床症状和肺功能,具有临床应用价值。

Objective To explore the clinical effect, symptom relief, and pulmonary function value of Zhisou powder and Sanzi Yangqin decoction on senile pneumonia.Methods A total of 150 elderly patients with pneumonia admitted to our hospital from January 2018 to February 2021 were randomly divided into an experimental group(n = 75) and a control group(n = 75). The control group was treated with conventional western medicine. The experimental group was treated with Zhisou powder and Sanzi Yangqin decoction on the basis of the control group. The clinical efficacy, symptom relief time, and pulmonary function before and after treatment [forced expiratory volume in the first second(FEV1) and forced vital capacity(FVC)] were compared between the two groups. t-test and χ^(2)test were used for the comparison between the two groups.ResultsThe total effective rate of the experimental group was 94.67%, higher than that of the control group(80.00%)(χ^(2)=7.292, P = 0.007). The disappearance time of expectoration and cough, the absorption time of inflammation, and the disappearance time of lung rales in the experimental group were(5.12 ± 0.42) d,(8.10 ± 0.58) d, and(8.68 ± 0.53) d respectively,which were shorter than those in the control group:(7.15 ± 0.65) d,(11.02 ± 0.89) d, and(6.98 ± 0.46) d,(t = 22.717, 23.805,20.979, all P < 0.01). After treatment, the FEV1and FVC of the experimental group were(2.87 ± 0.18) L and(4.02 ± 0.25) L respectively, which were higher than those of the control group:(1.76 ± 0.14) L and(2.65 ± 0.21) L(t = 42.155, 36.339, both P < 0.01).Conclusion Zhisou powder combined with Sanzi Yangqin decoction can improve clinical efficacy, improve clinical symptoms and lung function, and have clinical application value.