肠道细菌与乳腺癌转移关系的研究进展

Research progress on the relationship between intestinal bacteria and metastasis of breast cancer

乳腺癌是全世界女性最常见的肿瘤之一,也是女性癌症相关死亡的主要原因,其主要死亡原因为转移。随着肿瘤研究的发展以及诊断技术的进步,肠道菌群被发现与乳腺癌发生发展相关,并在物质代谢、对免疫系统的调节、化疗、放疗及中医药治疗的影响等过程中参与乳腺癌的转移。文章综述了肠道菌群与乳腺癌转移之间的相关性及机制,以期指导临床与科研工作。

Breast cancer is one of the most common tumors among women in the world,and it is also the main cause of cancer related death for women.The main cause of death is metastasis.With the development of tumor research and the progress of diagnostic technology,intestinal flora has been found to be related to the occurrence and development of breast cancer,and participate in the metastasis of breast cancer in the process of material metabolism,regulation of the immune system,chemotherapy,radiotherapy and the impact of traditional Chinese medicine treatment.This article reviewed the correlation and mechanism between intestinal flora and breast cancer metastasis,in order to guide clinical and scientific research work.