空间组学技术在医学研究中的应用进展

Application progress of spatial omics technology in medical research

空间组学技术是现代热点生物技术,其应用领域广泛,影响力也日益剧增。本文介绍了空间代谢组学技术、空间蛋白质组学技术、空间转录组学技术的概念,以及它们分别在药物靶点分析、组织空间分布和细胞空间定位上的技术特点。并进一步重点阐述了这几种空间组学技术在代谢性疾病、肿瘤疾病,和传染性疾病中的最新研究进展。面对人工智能时代,空间组学技术有望对人类研究和治疗疾病提供有力的技术支持。

Spatial omics technology is a modern hot biotechnology,which has a wide range of applications and increasing influence.This paper introduces the concepts of spatial metabolomics,spatial proteomics and spatial transcriptomics,as well as their technical characteristics in drug target analysis,tissue spatial distribution and cell spatial localization.This paper further focuses on the latest research progress of these spatial omics technologies in metabolic diseases,tumor diseases and infectious diseases.It is expected to provide powerful support for the research and treatment of diseases in the era of artificial intelligence.