基于反向散射的定量超声生物标记物在妊娠妇女宫颈微结构变化中的诊断价值研究

Study of Diagnosis Value of Quantitative Ultrasound Biomarkers Based on Backscatter in Cervical Microstructure of Pregnant Women

目的研究基于反向散射的定量超声生物标记物在妊娠妇女宫颈微结构变化中的诊断价值。方法选取2020年7—12月在阳江市第三人民医院产检的孕妇40例,将其分为两组,早产组20例妇女在孕早期(妊娠5~14周)即终止妊娠;足月组中20例在孕晚期(37~41周)足月引产。均接受了超声检查,统计分析两组孕妇的衰减系数(attenuation coefficient,SAC)和平均背向散射功率差(average backscattering power difference,mBSPD),并分析早产组孕妇的漏斗形成情况。结果早产组孕妇20例中,在漏斗形状方面,U型、V型、Y型、T型分别占40.00%、30.00%、20.00%、10.00%。早产组孕妇的SAC和mBSPD均低于足月组,差异有统计学意义(P<0.05)。结论基于反向散射的定量超声生物标记物在妊娠妇女宫颈微结构变化中的诊断价值较高。

Objective To study the diagnosis value of quantitative ultrasound biomarkers based on backscatter in the changes of cervical microstructure in pregnant women.Methods A total of 40 cases of pregnant women who underwent prenatal examination in Yangjiang Third People’s Hospital from July to December 2020 were divided into two groups.One group was premature delivery group,20 cases of women terminated pregnancy in the early pregnancy(5~14 weeks of pregnancy),and 20 cases in the full-term group induced labor in the late pregnancy(37~41 weeks of pregnancy).The attenuation coefficient(SAC)and average backscattering power difference(mBSPD)of pregnant women in the two groups were statistically analyzed,and the funnel formation of pregnant women in the preterm delivery group was analyzed.Results Among the 20 cases of pregnant women in the preterm delivery group,in terms of funnel shape,U type,V type,Y type and T type accounted for 40.00%,30.00%,20.00%and 10.00%respectively.The SAC and mBSPD of pregnant women in the preterm delivery group were lower than those in fullterm group,and the difference was statistically significant(P<0.05).Conclusion Quantitative ultrasound biomarkers based on backscatter have high diagnosis value in the changes of cervical microstructure in pregnant women.