特发性膜性肾病心血管并发症的机制研究的进展

Research progress on mechanisms of cardiovascular complications in idiopathic membranous nephropathy

特发性膜性肾病(IMN)为常见免疫相关性肾病,伴血栓高发风险,会导致终末期肾病的进展及死亡发生,临床目前侧重静脉血栓事件的研究,对于心血管事件的发生机制并未作系统阐述。本文就IMN心血管并发症的机制研究的进展作一综述,以期为预防IMN血栓事件的发生及进展提供新方向。

Idiopathic membranous nephropathy(IMN) is a common immune-related nephropathy associated with a high risk of thrombosis, which can lead to progression and death of end-stage renal disease. Currently, clinical studies focus on venous thrombosis events, and mechanism of cardiovascular events has not been systematically elaborated. The present article makes a review on research progress on mechanisms of cardiovascular complications in IMN, aiming at providing new directions for preventing occurrence and progression of thrombus events of IMN.