动物源性食品中氟喹诺酮类药物残留现状和检测方法研究进展

Research Progress of Current Status and Detection Methods of Fluoroquinolones in Animal Derived Food

氟喹诺酮类药物廉价、高效,广泛用于预防和治疗畜禽及水产养殖中各种常见的细菌性疾病。近年来,动物性食品中氟喹诺酮类药物残留不合格情况严重,其中恩诺沙星残留不合格率位居榜首且涉及的动物性食品种类多,亟需探究导致不同养殖动物药物残留消除差异的原因,制定其精准的用药指南和停药期规定。文章通过综述食品中氟喹诺酮类药物的残留形势和国内外报道的氟喹诺酮类药物残留检测方法,并比较各种检测方法的优缺点、适用场所及应用前景等,以期为食品性动物建立科学、高效的控制体系提供参考。

Fluoroquinolones are a kind of cheap and effective antimicrobial drugs and widely used in the prevention and treatment of common bacterial diseases in livestock, poultry and aquaculture industry. In recent years,the unqualified situation of fluoroquinolone residues was serious in animal derived food, among which enrofloxacin residues have the highest unqualified rate and cover a wide range of animal food. There is an urgent need to explore the reasons for the differences of drug residues elimination in different farmed animals, and formulate precise medication guidelines and withdrawal periods for different animals. In this paper, the situation of fluoroquinolone residues in food and detection methods of fluoroquinolone residues reported at home and abroad were reviewed, and the advantages and disadvantages, applicable sites and application prospects of various detection methods were compared, in order to provide reference for the establishment of scientific and efficient control system for food animals.