五音调神法在脑卒中后抑郁伴睡眠障碍患者中的应用效果

Application effect of five-tone god method in patients with post-stroke depression and sleep disorders

目的探讨五音调神法应用于脑卒中后抑郁伴睡眠障碍患者的效果。方法选取开封市中医院脑病科2020年7月至2022年4月95例脑卒中后抑郁伴睡眠障碍患者,以抽签法分组。两组均给予基础治疗,对照组47例给予认知行为疗法干预,观察组48例给予联合五音调神法干预。对比两组患者多导睡眠图参数变化、神经递质水平、希望水平及抑郁情况。结果干预后观察组睡眠总时间(401.92±33.39)min、睡眠效率(81.22±5.27)%、REM潜伏期(147.68±18.90)min、5-羟色胺(5-HT)(126.51±9.68)ng/mL、Herth希望量表(HHI)积极行为评分(12.67±1.79)分、行为态度评分(13.33±1.75)分、积极关系评分(13.54±1.71)分高于对照组(343.14±26.17)min、(73.30±4.51)%、(111.55±14.88)min、(103.91±7.85)ng/mL、(9.38±1.09)分、(10.94±1.51)分、(10.47±1.12)分;觉醒时间(51.37±10.97)min、觉醒次数(2.04±0.82)次、汉密尔顿抑郁量表(HAMD)(5.12±1.30)分低于对照组(82.16±26.17)min、(5.11±1.43)次、(8.54±1.99)分,差异有统计学意义(P<0.05)。结论应用五音调神法对脑卒中后抑郁伴睡眠障碍患者进行干预,可有效改善睡眠质量和抑郁情绪,调节5-HT因子水平,提升希望水平。

Objective To explore the effect of the method of five-tone to regulate the mind in patients with post-stroke depression and sleep disorder.Methods From July 2020 to April 2022,95 patients with post-stroke depression and sleep disorders were selected from the Department of Encephalopathy,Kaifeng Hospital of Traditional Chinese Medicine and divided into groups by drawing lots.Both groups were given basic treatment,47 cases in the control group were given cognitive behavioral therapy intervention,and 48 cases in the observation group were given combined five-tone and mind regulation intervention.The changes of polysomnography parameters,neurotransmitter levels,hope levels and depression were compared between the two groups.Results After intervention,the total sleep time(401.92±33.39)min,sleep efficiency(81.22±5.27)%,REM latency(147.68±18.90)min,5-TH(126.51±9.68)ng/mL,HHI positive behavior score(12.67±1.79)points,behavior attitude score(13.33±1.75)points,positive relationship score(13.54±1.71)points in the observation group were higher than those in the control group(343.14±26.17)min,(73.30±4.51)%,(111.55±14.88)min,(103.91±7.85)ng/mL,(9.38±1.09)points,(10.94±1.51)points(10.47±1.12)points;The awakening time(51.37±10.97)min,awakening times(2.04±0.82)times,and HAMD(5.12±1.30)points in the observation group were lower than those in the control group(82.16±26.17)min,(5.11±1.43)times,and(8.54±1.99)points,with statistically significant differences(P<0.05).Conclusion The intervention of five-tone and mind regulating method in patients with post-stroke depression and sleep disorder can effectively improve sleep quality and depressive mood,regulate the level of 5-HT factor and raise the level of hope.