肿瘤长径及高血压与心脏黏液瘤栓塞事件发生的相关性

Correlation of tumor length and hypertension for cardiac myxoma embolism events

目的:探讨心脏黏液瘤患者的肿瘤特征、是否高血压与发生栓塞事件的关系。方法:收集2004年10月至2020年10月于华北理工大学附属开滦总医院确诊的心脏黏液瘤患者31例,依照患者的临床特征将其分为栓塞组(n=8)和非栓塞组(n=23)。收集患者相关临床指标,进行Logistic回归分析。结果:两组间肿瘤位置、肿瘤长径、是否合并高血压存在显著差异(P<0.05)。肿瘤长径、合并高血压与栓塞事件成正相关(P<0.05)。肿瘤长径、合并高血压是栓塞事件的独立危险因素(P<0.05)。Logistic回归模型预测栓塞事件发生概率值的ROC曲线下面积AUC为0.902(95%CI:0.782~1.000,P<0.01)。结论:肿瘤长径、高血压可以影响心脏黏液瘤患者栓塞事件的发生。联合上述指标构建回归模型,可以提高评估心脏黏液瘤患者发生栓塞事件的准确性。

Objective:To explore the relationship between tumor characteristics, hypertension and embolic events in patients with cardiac myxoma.Methods:A total of 31 patients with cardiac myxoma diagnosed in Kailuan General Hospital Affiliated to North China University of Science and Technology from October 2004 to October 2020 were collected and divided into embolization group(n=8) and non-embolization group(n=23) according to the clinical characteristics of the patients.The relevant clinical indicators of the patients were collected, and Logistic regression analysis was performed.Results:There were significant differences between the two groups in tumor location, tumor length, and hypertension(P<0.05).There was a positive correlation between tumor length, hypertension and embolism events(P<0.05).Tumor length and hypertension were independent risk factors for embolism events(P<0.05).The area under the ROC curve(AUC) of the logistic regression model for predicting the probability of embolism events was 0.902(95%CI:0.782~1.000,P<0.01).Conclusion:Tumor length and hypertension affect the occurrence of embolism events in patients with cardiac myxoma.Combining these indicators to construct a regression model can improve the accuracy of evaluating embolic events in patients with cardiac myxoma.