角膜屈光术后干眼和神经病理性眼痛的发病机制

Pathogenesis of dry eye and neuropathic ocular pain after keratorefractive surgery

随着角膜屈光手术的盛行,术后的并发症也日益受到重视。其中干眼是最常见的并发症,且部分患者存在慢性眼痛,严重影响患者术后满意度。近年来研究发现泪液功能单位障碍在角膜屈光术后干眼的发病机制中起核心作用。同时,研究者逐渐关注角膜神经痛与角膜屈光术后眼痛的关系,试图从此角度理解角膜屈光术后眼痛的病理机制。

With the prevalence of keratorefractive surgery,postoperative complications attract increasing attention from ophthalmologists.Among them,dry eye is the most common complication.What’s more,some patients suffer chronic ocular pain,which seriously affects the postoperative satisfaction of patients.Recent studies have found that tear functional units dysfunction plays a core role in the pathogenesis of dry eye after keratorefractive surgery.Meanwhile,researchers pay more and more attention to the relationship between neuropathic corneal pain and chronic ocular pain after corneal refractive surgery,trying to understand the pathological mechanism of ocular pain after corneal refractive surgery from this point of view.