两种山药化学成分及药理活性比较

Comparison of chemical constituents and pharmacological activities of twoyams

通过对安顺山药与河南铁棍山药的化学成分含量(薯蓣皂苷、总黄酮、尿囊素、多糖)及药理活性(抗菌性、清除自由基率)的比较,结果表明:河南铁棍山药的薯蓣皂苷、总黄酮、尿囊素、多糖分别比安顺山药高0.26%、0.08%、0.08%、1.02%,但两种山药除多糖含量差异显著(P<0.001)外,其余含量差异均不显著;铁棍山药多糖对金黄色葡萄球菌、大肠杆菌抑菌作用均略强于安顺山药;安顺山药的粗黏液质体积达到50mL时,对DPPH·和·OH的清除能力均高于河南铁棍山药,分别为83%和73%。结论:与河南铁棍山药相比,安顺山药中薯蓣皂苷、总黄酮、尿囊素、多糖等化学成分含量虽略低,但其中多糖抗菌能力与铁棍山药接近,其黏液质达到50 mL时,体外抗氧化能力优于铁棍山药。

Comparating the contents of chemical composition(dioscin、totalflavonoids、allantoin、polysaccharides)andpharmacologicalactivities(antibacterial and the scavenging rates of free radicals)ofAnshun Chinese Yam with Chinese yam,the results show the diosgenin、totalflavonoids、allantoin、polysaccharidesofChinese yamare 0.26%、0.08%、0.08%、1.02%higher than those ofAnshun Chinese Yam,but there was significant difference inpolysaccharidescontent between the two yams(P<0.001),the difference of other contents was not ignificant.The bacteriostatic effect of Chinese yampolysaccharide on Staphylococcus aureus and Escherichia coil was slightly stronger than that of Anshun Chinese Yam.When the volume of crude viscosity of Anshun Chinese Yamreaches 50mL,thescavenging ability of DPPHand hydroxyl radical were higher than these ofChinese Yam.They were 83%and70%,respectively.Conclusion:Compared withChinese Yam,the content ofdioscin、totalflavonoids、allantoin、polysaccharidesin Anshun Chinese Yamwas slightly lower,but the antibacterial ability of polysaccharide is close to that of Chinese Yam,and the antioxidant ability was better than that of Chinese Yamwhen the mucilage reached 50mL.