2-Methoxyjuglone, a Promising Bioactive Compound for Pharmaceutical and Agricultural Purposes: A Review

2-Methoxyjuglone,a member of the 1,4-naphthoquinone family,was first obtained through semi-synthesis based on 2-hydroxyjuglone as the precursor in 1966.It has been isolated and identified from different plant species of the Juglandaceae,Sterculiaceae,and Proteaceae families.2-Methoxyjuglone has been demonstrated to possess a wide range of biological activities,including antitumor,antifungal,and antibacterial activities;in addition,it has been shown to poison fish and inhibit seed germination.These properties make 2-methoxyjuglone a promising bioactive compound for pharmaceutical and agricultural purposes.This review article provides an overview of the current research progress on 2-methoxyjuglone for the first time,with a primary focus on the plant sources,extraction,identification,synthesis,and biological activities associated with this compound for further development.