经鼻高流量氧疗应用于前列腺穿刺活检舒芬太尼与丙泊酚静脉复合麻醉中的效果分析

Effect Analysis of Transnasal High Flow Oxygen Therapy in Combined Intravenous Anesthesia of Sufentanil and Propofol for Prostate Biopsy

目的:探讨经鼻高流量氧疗应用于前列腺穿刺活检舒芬太尼与丙泊酚静脉复合麻醉中的效果。方法:选择2021年1月-2022年6月长江大学附属第一医院收治的102例前列腺穿刺活检患者,以电脑随机数字表法将其分为常规组和试验组,各51例。常规组采用文丘里面罩氧疗法应用于前列腺穿刺活检舒芬太尼与丙泊酚静脉复合麻醉。试验组采用经鼻高流量氧疗应用于前列腺穿刺活检舒芬太尼与丙泊酚静脉复合麻醉。比较两组麻醉诱导前(T_(1))、麻醉诱导后(T_(2))、意识清醒时(T_(3))、完全苏醒时(T_(4))动脉血氧分压(PaO_(2))、动脉二氧化碳分压(PaCO_(2))、麻醉效果、缺氧事件及不良反应发生情况。结果:两组缺氧事件、托下颌、面罩加压给氧发生率比较,差异均无统计学意义(P>0.05)。T_(1)与T_(4)时,两组PaO_(2)、PaCO_(2)水平比较,差异均无统计学意义(P>0.05)。T_(2)与T_(3)时,两组PaO_(2)水平均低于T_(1)时,PaCO_(2)水平均高于T_(1)时,且试验组PaO_(2)水平均高于常规组,PaCO_(2)水平均低于常规组(P<0.05)。试验组麻醉效果优良率为94.12%,高于常规组的78.43%(P<0.05)。试验组不良反应发生率为5.88%,低于常规组的21.57%(P<0.05)。结论:经鼻高流量氧疗应用于前列腺穿刺活检舒芬太尼与丙泊酚静脉复合麻醉中效果显著,可改善患者的血气指标,降低不良反应率,值得推广应用。

Objective:To explore the effect of transnasal high flow oxygen therapy in combined intravenous anesthesia of Sufentanil and Propofol for prostate biopsy.Method:A total of 102 patients with prostate puncture biopsy admitted to the First Affiliated Hospital of Changjiang University from January 2021 to June 2022 were selected,they were divided into the conventional group and the experimental group by computer random number table method,with 51 cases in each group.Venturi mask oxygen therapy was given for prostate biopsy with Sufentanil combined with Propofol intravenous anesthesia in the conventional group.In the experimental group,transnasal high flow oxygen therapy was applied to Propofol and Sufentanil intravenous anesthesia for prostate biopsy.Arterial partial oxygen pressure (PaO_(2)) and arterial partial carbon dioxide pressure (PaCO_(2)) before anesthesia induction (T_(1)),after anesthesia induction (T_(2)),when conscious (T_(3)) and when full recovery (T_(4)),anaesthesia effect,anoxic events and adverse reactions were compared between the two groups.Result:There were no significant differences in the incidence of hypoxia events,jaw support and mask pressure oxygen administration between the two groups (P>0.05).At T_(1)and T_(4),there were no significant differences in PaO_(2)and PaCO_(2)levels between the two groups (P>0.05).The levels of PaO_(2)at T_(2)and T_(3)were lower than those at T_(1),the levels of PaCO_(2)were higher than those at T_(1),and PaO_(2)in experimental group were higher than those in conventional group,PaCO_(2)were lower than those in conventional group(P<0.05).The rate of excellent anesthetic effect in experimental group was 94.12%,which was higher than 78.43%in conventional group (P<0.05).The incidence of adverse reactions in experimental group was 5.88%,which was lower than 21.57%in conventional group (P<0.05).Conclusion:Transnasal high flow oxygen therapy is effective in the combined intravenous anesthesia of Sufentanil and Propofol for prostate biopsy.It can improve the blood gas index of patients and reduce the adverse reaction rate.It is worth popularizing.