光学相干层析技术在眼科手术导航方面的研究进展

Review of the development of optical coherence tomography imaging navigation technology in ophthalmic surgery

在眼科显微手术中,传统的术中成像方式由于缺少深度信息,限制了内部结构和手术器械的可视化。光学相干层析成像技术(OCT)是一种非接触式断层成像技术,由于其能提供深度信息、非侵入、成像快、分辨率高等优点,被广泛应用于眼科手术的术中导航。典型的OCT设备可分为手持OCT和显微镜集成OCT。本文简要介绍了时域OCT和频域OCT的原理和发展,回顾了OCT眼科手术导航设备的发展历程,并对各个类别中有代表性的OCT系统进行了介绍,对其成像原理、性能、优缺点等进行了描述和对比,最后对该技术在眼科手术中的应用做出了总结和展望。

During ophthalmic microsurgery,the visualization of internal structures is limited by traditional intraoperative imaging methods due to their lack of depth information.Optical coherence tomography(OCT)is a non-contact tomographic imaging technique that is widely used for intraoperative navigation in ophthalmic surgery because of its ability to provide depth information,non-invasiveness,fast imaging,and high resolution.Typical OCT devices can be divided into handheld OCT and microscope-integrated OCT.This article briefly introduces the mechanism and development of time domain OCT and fourier domain OCT,reviews the development of OCT ophthalmic surgical navigation devices,introduces representative OCT systems in each category,describes and compares their imaging principles,performance,advantages,and disadvantages,and finally concludes with a summary and outlook on the applications of this technology in ophthalmic surgery.