基于数据挖掘技术探讨针刺治疗男性不育症的选穴循经规律

An exploration of the rules of acupoint selection and meridian circulation in the treatment of male infertility based on data mining technology

目的运用数据挖掘技术分析针刺治疗男性不育症(MI)的选穴循经规律。方法制定文献检索策略,检索数据库包含中国期刊全文数据库、万方数据库、维普资源系统以及Pubmed、Embase、Web of Science英文数据库。按照纳入及排除标准进行文献筛选,建立针刺治疗MI的处方数据库。利用SPSS Modeler 18.0以及Gephi 0.9.1软件分别进行描述性分析、关联规则分析和核心腧穴分析。结果文献检索后最终纳入中文文献22篇,英文文献7篇;循经频次前5分别是任脉、足太阳膀胱经、足太阴脾经、足阳明胃经、督脉;关联规则分析显示支持度>30%的穴位配伍有16个;核心腧穴分别为关元、肾腧、三阴交、气海、足三里、百会、血海、太溪。结论针刺治疗MI的治疗原则以补肾健脾、调和阴阳、益气养血为主。常用配伍为正面关元-气海-三阴交,背面为肾俞-次髎,足三里可兼配之;循经以任督二脉、膀胱经以及脾、胃二经为主。

Objective Data mining technology was used to explore the rules of acupoint selection and meridian circulationin the treatment of male infertility(MI).Methods Formulate literature retrieval strategies,and the retrieval databases include Chinese Journal Full-text Database,Wangfang Database,VIP Resource System,Pubmed,Embase and Web of Science.The literature was screened according to inclusion and exclusion criteria,and the prescription database of acupuncture treatment of MI was established.Descriptive analysis,association rule analysis and core acupoint analysis were implemented by using SPSS Modeler 18.0 and Gephi 0.9.1 software respectively.Results Literature retrieval,22 Chinese and 7 English literatures were finally included.The top 5 meridian frequencies were conception vessel,bladder meridian of foot-Taiyang,spleen meridian of foot-Taiyin,stomach meridian of foot-Yangming and governor vessel.Association rule analysis showed that there were 16 acupoints with support>30%.The core acupoints were Guanyuan(CV4),Shenshu(BL23),Sanyinjiao(SP6),Qihai(CV6),Zusanli(ST36),Baihui(DU20),Xuehai(SP10)and Taixi(KI3).Conclusions Acupuncture in the treatment of MI mainly to tonify the kidney and spleen,harmonize Yin and Yang and nourish Qi and Blood.Commonly used compatibility is Guanyuan-Qihai-Sanyinjiao in the front and Shenshu-Ciliao in the back,and Zusanli(ST36)can be used in both acupoints compatibility above.The main channels were conception vessel,governor vessel,bladder meridian of foot-Taiyang,spleen meridian of foot-Taiyin and stomach meridian of foot-Yangming.