急性非ST段抬高型心肌梗死患者合并心境障碍相关因素分析

Analysis of mood disorder and its related factors in patients with acute non-st-segment elevation myocardial infarction before percutaneous coronary intervention

目的:研究非ST段抬高型急性心肌梗死(NSTEMI)经皮冠状动脉介入治疗(PCI)术前,人群不同程度的焦虑抑郁压力现状,并分析其影响因素。方法:纳入270例急诊NSTEMI患者,于入院后进行一般情况调查及心理测评,并收集数据包括:性别、年龄、职业、既往慢性病史、TC、LDL-C、CK、BNP等。从多个方面对于患者术前心境障碍的相关影响因素进行分析,并预测其高危因素。结果:NSTEMI患者PCI术前焦虑比例(69.2%)、抑郁比例(35.9%)、压力比例(23.2%)较常人均明显升高。性别、吸烟史、CK、LDL是影响患者术前焦虑的相关因素;性别是影响NSTEMI患者PCI术前抑郁的相关因素;性别、吸烟史、TC、LDL是影响患者术前压力的相关因素。结论:女性、有脑血管病史是患者焦虑的危险因素;女性、高龄是患者抑郁的危险因素;女性、TC升高、有陈旧心肌梗死史是患者压力的危险因素。

Objective:To explore the present situation of depression,anxiety and stress symptoms and its related influencing factors in patients with acute non-ST-segment elevation myocardial infarction(NSTEMI)before percutaneous coronary intervention(PCI).Methods:A total of 270 patients with NSTEMI,who presented to the Cardiac Center of Beijing Anzhen Hospital from May 2021 to April 2022 were selected as the research objects.All the patients were evaluated by The Depression Anxiety Stress Scale(DASS-21)before PCI,while we collected data including gender,age,occupation,past medical history,TC,LDLC,CK,BNP.etc.The influencing factors were analyzed,and the risk factors of emotional disorder symptoms before PCI were analyzed by logistic regression.Results:The rates of anxiety(69.2%),depression(35.9%)and stress(23.2%)in our patients were significantly higher than normal people.Gender,history of smoking and CK,LDL were independent factors affecting anxiety(P<0.05);Gender was independent factors affecting depression(P<0.05);Gender,history of smoking,TC,LDL were independent factors affecting stress(P<0.05).Conclusions:female,normal TC and history of cerebrovascular disease were the risk factors of anxiety;Female,advanced age,tall and without history of diabetes were the risk factors of depression;female,TC increasing,history of old myocardial infarction and no diabetes were the risk factors of stress.