耳穴贴压联合通淋促排汤治疗泌尿系腔内钬激光术后残留结石的疗效观察

Efficacy observation of auricular points sticking plus Tong Lin Cu Pai decoction for residual urinary stones after holmium laser lithotherapy

目的观察耳穴贴压磁珠联合通淋促排汤治疗泌尿系腔内钬激光术后残留结石临床疗效。方法共纳入160例泌尿系腔内钬激光术后残留结石患者,将其按随机数字表法分成对照组和观察组,每组80例。对照组患者术后多饮水,适当运动;观察组在对照组基础上采用耳穴贴压磁珠联合通淋促排汤治疗。比较两组临床疗效、残留结石排出时间及疼痛消失时间,比较两组治疗前后各项中医证候积分和血肝肾功能指标水平的变化,比较两组治疗后炎症因子水平以及并发症和不良反应的发生情况。结果观察组总有效率高于对照组(P<0.05)。观察组患者残留结石排出时间及疼痛消失时间均短于对照组(P<0.05)。治疗后,两组各项中医证候积分均降低(P<0.05),且观察组低于对照组(P<0.05)。观察组治疗后血清白介素-6、超敏C反应蛋白和肿瘤坏死因子-α水平均低于对照组(P<0.05)。两组治疗前后肝肾功能指标比较,差异无统计学意义(P>0.05)。观察组并发症发生率低于对照组(P<0.05)。两组均未见不良反应发生。结论耳穴贴压磁珠联合通淋促排汤治疗泌尿系腔内钬激光术后残留结石可有效促使结石排出,改善患者症状,可降低血清炎症因子水平,且治疗过程安全。

Objective To observe the clinical efficacy of auricular point sticking with magnetic beads plus Tong Lin Cu Pai decoction in treating residual urinary stones after holmium laser lithotherapy.Method This trial recruited 160patients with residual urinary stones after receiving holmium laser lithotherapy.They were divided into a control group and an observation group using the random number table method,with 80 cases in each group.Patients in the control group were told to drink more water and take exercise moderately.The observation group received additional auricular point sticking with magnetic beads and Tong Lin Cu Pai decoction.The two groups were compared in terms of clinical efficacy,time of evacuating residual stones,and time of pain relief.Changes in the symptom scores of traditional Chinese medicine(TCM)and blood liver and kidney function indicators,inflammatory factor levels,and adverse reactions were also compared after treatment.Result The total effective rate was higher in the observation group than in the control group(P<0.05).The observation group took a shorter time to discharge residual stones and relieve the pain than the control group(P<0.05).After treatment,the TCM symptom scores dropped in both groups(P<0.05)and were lower in the observation group than in the control group(P<0.05).After treatment,the levels of serum interleukin-6,hypersensitive C-reactive protein,and tumor necrosis factor-αin the observation group were lower than those in the control group(P<0.05).There were no significant differences in the liver or kidney function indexes between the two groups before and after treatment(P>0.05).The observation group had a lower complication rate than the control group(P<0.05).Neither group had adverse reactions.Conclusion For residual urinary stones after holmium laser lithotherapy,auricular point sticking with magnetic beads plus Tong Lin Cu Pai decoction can boost the discharge of stones,improve symptoms,and lower serum inflammatory factor levels,and the treatment process is safe.