基于血流储备分数角度评估定量血流分数的准确性及最新研究进展

Accuracy and latest research progress of quantitative flow ratio evaluation based on fractional flow reserve

关于冠状动脉病变的新型功能学评估方法现已受到国内外广泛关注。定量血流分数(quantitative flow ratio,QFR)作为一种新型功能学评估技术,目前已有许多临床试验证实了其在诊断冠状动脉狭窄病变所致心肌缺血准确性及可行性方面的临床价值。相比传统的诊断冠状动脉狭窄病变的金标准血流储备分数(fractional flow reserve,FFR),QFR具备操作简便、省时、低成本等优势。该文对FFR和QFR诊断准确性的对比及临床研究进展等展开综述,旨在探讨QFR有无可能替代FFR成为冠状动脉病变的功能学评估手段并指导临床血运重建。

New functional evaluation methods for coronary artery lesions have received widespread attention at home and abroad.As a new functional evaluation technique,the clinical value of quantitative flow ratio(QFR)in the accuracy and feasibility of diagnosing myocardial ischemia caused by coronary artery stenosis has been confirmed in many clinical trials.Compared with the traditional gold standard fractional flow reserve(FFR)for diagnosing coronary artery stenosis,QFR has the advantages of simple operation,time-saving and low cost.This article reviews the comparison of the diagnostic accuracy of FFR and QFR and the progress of clinical research,aiming to explore whether QFR may replace FFR as a functional evaluation method of coronary artery disease and guide clinical blood circulation reconstruction.