氢吗啡酮与舒芬太尼应用于妇科手术术后镇痛中的效果对比

Effect Comparison of hydromorphone and sufentanil on postoperative analgesia in gynecological surgery

目的 对比氢吗啡酮与舒芬太尼应用于妇科手术患者术后镇痛中的效果。方法 选取于本院妇科行腹腔镜手术治疗的60例患者为研究对象,按照入院顺序将其分为对照组及研究组,每组30例。对照组采用舒芬太尼术后镇痛,研究组采用氢吗啡酮术后镇痛。对比两组术后不同时间不同状态下的疼痛情况及术后不良反应发生情况。结果 静息状态下,研究组T_(1)、T_(2)、T_(3)、T_(4)的疼痛视觉模拟评分(VAS)分别为(1.89±0.61)、(1.57±0.50)、(0.88±0.28)、(0.72±0.25)分,均低于对照组的(2.79±0.73)、(2.58±0.74)、(1.71±0.52)、(0.97±0.37)分;活动状态下,研究组T_(1)、T_(2)、T_(3)、T_(4)的VAS评分分别为(2.47±0.82)、(2.15±0.71)、(1.49±0.47)、(1.32±0.41)分,均低于对照组的(3.52±0.91)、(3.36±0.75)、(2.54±0.69)、(2.26±0.62)分,差异有统计学意义(P<0.05)。研究组术后不良反应发生率为6.67%,明显低于对照组的26.67%,差异有统计学意义(P<0.05)。结论 妇科手术术后镇痛中应用氢吗啡酮的效果更佳、不良反应发生率更低,值得临床推广使用。

Objective To compare the effect of hydromorphone and sufentanil on postoperative analgesia in gynecological surgery patients. Methods 60 patients who underwent laparoscopic surgery in gynecology department of our hospital were selected as the research objects, and were divided into a control group and a study group according to the order of admission, with 30 cases in each group. Sufentanil was used for postoperative analgesia in the control group, and hydromorphone was used in the study group.The pain at different conditions in different time and the occurrence of postoperative adverse reactions were compared between the two groups. Results At rest, the pain visual analogue scale(VAS) scores of T1, T2, T3and T4were(1.89±0.61),(1.57±0.50),(0.88±0.28) and(0.72±0.25) points, respectively, which were lower than(2.79±0.73),(2.58±0.74),(1.71±0.52) and(0.97±0.37)points in the control group;in the active state, the VAS scores of T1, T2, T3and T4were(2.47±0.82),(2.15±0.71),(1.49±0.47)and(1.32±0.41) points, respectively, which were lower than(3.52±0.91),(3.36±0.75),(2.54±0.69),(2.26±0.62) points in the control group, and the differences were statistically significant(P<0.05). The incidence of postoperative adverse reactions in the study group was 6.67%, significantly lower than 26.67% in the control group, and the difference was statistically significant(P<0.05).Conclusion The effect of hydromorphone in postoperative analgesia of gynecological surgery is better and the incidence of adverse reactions is lower.