摘要
口腔遗传病与罕见病多表现为多器官或组织的结构异常或功能障碍,具有患病率低、临床特征复杂多样、病情较重的特征,是口腔诊治的难点。该文回顾了口腔遗传病与罕见病的有关概念,相关学科在国内外的发展以及国内目前针对此类疾病的诊治现状,并就口腔遗传病与罕见病的序列治疗、人文关怀和伦理等方面,分析未来口腔遗传病与罕见病值得关注的若干问题和研究趋势。
Oral genetic diseases and rare diseases are characterized by structural abnormalities or dysfunction of multiple organs or tissues,low prevalence,complex,diverse and severity clinical features,which is a difficult point in the regular dental practice.This article reviews the concept of oral genetic diseases and rare diseases,the development of related disciplines at home and abroad,and the current situation of diagnosis and treatment of such kinds of diseases in China.The following issues and clinical research trends in the future are emphasized such as sequential treatment,humanistic care,and ethics of oral genetic diseases and rare diseases.
作者
段小红
DUAN Xiaohong(State Key Laboratory of Military Stomatology&National Clinical Research Center for 0ral Diseases&Shaanxi Key Laboratory of Stomatology,Department of Oral Biology,Clinic of Oral Rare Diseases and Genetic Diseases,The Third Affiliated Hospital of Air Force Medical University,Xi’an,710032,China)
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2023年第1期5-10,共6页
Journal of Practical Stomatology
基金
国家自然科学基金(编号:81974145,81771052)。
关键词
遗传病学
遗传病
罕见病
序列治疗
牙
颅颌面
Genetics
Hereditary diseases
Rare diseases
Sequential therapy
Tooth
Craniofacial