血清铁蛋白与不良妊娠结局关系的研究进展

Research progress on the Relationship between serum ferritin and adverse pregnancy outcomes

目前铁缺乏症(ID)在全世界呈现高流行率,尤其是妊娠期女性。在孕期母亲和胎儿的生理需求不断增加,铁的需求量也会有所增加。在发达国家,育龄妇女的ID患病率在10%~33%,在发展中国家及不发达国家ID患病率更甚。临床需要将ID的筛查提前至备孕期或孕早期。而血清铁蛋白(SF)是评估ID敏感性和特异性的生物标志物,也是铁储存的指标之一。本文综述回顾分析铁蛋白与妊娠期相关并发症及新生儿结局关系的研究进展。

Iron deficiency(ID)has a high prevalence worldwide,especially in women during pregnancy.During pregnancy,the physical demands of the mother and fetus increase,so does the need for iron.In developed countries,the prevalence of iron deficiency(ID)among women of childbearing age ranges from 10% to 33%,and it is self-evident that the prevalence of iron deficiency is even greater in developing and underdeveloped countries.Previous studies have shown that these epigenetic changes lead to the development of various chronic diseases in adulthood and can even be inherited from generation to generation.Therefore,screening for iron deficiency needs to be advanced to the first trimester or trimester.Serum ferritin(SF),which is the most sensitive and specific biomarker for the assessment of ID,is also one of the indicators of iron storage.This article reviews and analyzes the research progress of the relationship between ferritin and pregnancy-related complications and neonatal outcomes.