经上皮准分子激光角膜切削术的研究进展

Research progress of transepithelial photorefractive keratectomy

经上皮准分子激光角膜切削术(transepithelial photorefractive keratectomy,TPRK)是一种新型的角膜表面屈光手术,具有零切口、无接触、切削更精确等特点,可减少细胞凋亡,减轻术后疼痛,提高患者术后舒适度。TPRK矫正近视和近视散光术后具有良好的安全性、有效性、稳定性和可预测性。因无需制作角膜瓣,角膜生物力学更加稳定,且引入的像差更小,视觉质量更优,但术后干眼、角膜上皮延迟愈合、偏中心切削等相关并发症的预防仍需继续研究并完善。

Transepithelial photorefractive keratectomy is a new corneal surface refractive surgery.It has the characteristics of zero incision,no contact and more accurate cutting.It can reduce apoptosis and postoperative pain,and improve postoperative comfort of patients.TPRK has good safety,efficacy,stability and predictability after correction of myopia and myopic astigmatism.Because there is no need to make corneal flap,the corneal biomechanics are more stable,and introduces less aberration,and acquires better visual quality.However,the prevention of postoperative dry eyes,delayed healing of corneal epithelium,decentered ablation and other related complications prevention still need to be studied and improved.