家庭化个体多元复合声治疗对耳鸣伴听力损失患者的疗效及影响因素分析

Effects and influencing factors of family-oriented customized sound therapy on patients with tinnitus and hearing loss

目的 探究家庭化个体多元复合声治疗对耳鸣伴听力损失患者的有效性,并分析耳鸣伴听力损失患者疗效的影响因素。方法 利用四川省4家三甲医院的既往电子病历记录,回顾性分析2019年3月至2022年3月期间接受家庭化个体多元复合声治疗的212例耳鸣患者临床资料,收集耳鸣患者的人口学特征、听力损失相关和治疗前后的耳鸣障碍量表评分等资料。采用多因素二元逻辑回归分析疗效相关影响因素。结果 家庭化个体多元复合声治疗对耳鸣伴听力损失患者的总有效率为43.87%,治疗周期长于12个月的耳鸣患者的有效改善率(57.43%)显著高于治疗周期短于12个月的耳鸣患者(31.53%),单因素逻辑回归分析比值比(OR)值为2.93 (95%CI:1.67~5.14)。多因素逻辑回归分析提示治疗周期为影响家庭化个体多元复合声治疗效果的独立风险因素,OR值为2.23 (95%CI:1.09~5.00),患者年龄与声治疗疗效的OR值为1.03 (95%CI:1.01~1.05)。结论 研究表明家庭化个体多元复合声治疗可有效改善部分耳鸣患者的临床症状及恼人程度。其中,治疗周期是影响家庭化个体多元复合声治疗疗效的独立危险因素。临床医生应针对不同听力损失和耳鸣特征的耳鸣患者采用家庭化个体多元复合声治疗方案。

Objective To evaluate the efficacy of family-oriented customized sound therapy in patients with tinnitus in the absence or presence of hearing loss, and analyze the effects of related factors by sound therapy. Methods We retrieved electronic medical records from March 2019 to March 2022 from four hospitals in Sichuan province, and conducted a retrospective cohort study to analyze data on 212 patients with tinnitus who received family-oriented customized sound therapy. The demographic, hearing loss characteristics, and the tinnitus handicap inventory scores before and after treatments were extracted. Binary logistic regression was used to analyze the factors associated with efficacy. Results The effectiveness of family-oriented customized sound therapy for all patients with tinnitus and hearing loss was 43.87%. Patients treated for more than 12 months(57.4%) had a significantly higher percentage of improvement than those treated for less than 12 months(31.5%) with the odds ratio(OR) of 2.93(95%CI: 1.67-5.14). The multivariable regression analysis showed that there was significant difference in treatment cycles with an OR of 2.23(95%CI: 1.09-5.00) and the association of age with an OR of 1.03(95%CI: 1.01-1.09). Conclusion Family-oriented customized sound therapy can effectively improve the clinical symptoms and annoyance in patients with tinnitus. Treatment period is the main factor associated with the efficacy of family-oriented customized sound therapy. Clinicians are thus advised to adopt family-oriented customized sound therapy for patients diagnosed with different types of hearing loss and tinnitus.