产期孕妇B群链球菌感染情况和高危因素及对妊娠结局、新生儿的影响

Situation and risk factors of group B streptococcus infection in perinatal pregnant women and their effects on pregnancy outcome and neonates

目的分析围生期孕妇B群链球菌感染情况和高危因素及对妊娠结局、新生儿的影响。方法回顾性选取2020年12月至2021年12月赣州市妇幼保健院收治的780例围生期女性作为研究对象,按照有无感染分为对照组(720例)与观察组(60例),对照组未感染孕妇与观察组感染患者均采取细菌培养法,展开影响因素分析,比较两组孕妇的妊娠结局以及新生儿结局。结果两组孕妇的流产史以及合并妊娠期糖尿病指标比较,差异有统计学意义(P<0.05);采用logistic回归模型进行多因素分析,结果显示,合并妊娠期糖尿病(β=0.102,OR=1.598,95%CI=1.328~1.852)以及流产史(β=0.211,OR=1.251,95%CI=1.021~1.492)是围生期孕妇B群链球菌感染的独立危险因素(P<0.05)。观察组不良妊娠结局与新生儿不良结局总发生率均高于对照组,差异有统计学意义(P<0.05)。结论与围生期孕妇B群链球菌感染相关的高危因素较多,需做好预防,减少高危因素及对妊娠结局、新生儿的影响。

Objective To analyze the infection status and high-risk factors of group B streptococcus infection in perinatal pregnant women and their effects on pregnancy outcomes and neonates.Methods A total of 780 perinatal women admitted to Ganzhou Women and Children's Health Care Hospital from December 2020 to December 2021 were retrospectively selected as the research objects,they were divided into control group(720 cases)and observation group(60 cases)according to whether there was infection or not.The uninfected pregnant women in the control group and the infected patients in the observation group were all recieved bacterial culture,and the influencing factors were analyzed to compare the pregnancy outcomes and neonatal outcomes of the two groups.Results There were statistically significant differences between the two groups in terms of abortion history and indicators of diabetes complicating pregnancy(P<0.05).Multivariate analysis was performed using logistic regression model.Diabetes complicating pregnancy(β=0.102,OR=1.598,95%CI=1.328-1.852)and abortion history(β=0.211,OR=1.251,95%CI=1.021-1.492)were independent risk factors for group B streptococcal infection in perinatal pregnant women.The total incidences of adverse pregnancy outcomes and neonatal adverse outcomes in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion There are many high-risk factors associated with group B streptococcus infection in perinatal pregnant women,and prevention should be done to reduce the high-risk factors and their impact on pregnancy outcomes and neonates.