体外冲击波疗法治疗膝关节骨关节炎Meta分析

Extracorporeal shockwave therapy for knee osteoarthritis:a meta-analysis

目的:系统评价体外冲击波治疗膝关节骨关节炎的有效性。方法:检索CNKI、CBM、维普、万方、Pubmed数据库从建库截至2021年6月8日收录的有关体外冲击波疗法治疗膝关节骨关节炎的临床随机对照试验(Randomized controlled trial,RCT),由2名研究人员独立客观进行筛选、提取、评价,使用Revman 5.3软件对提取的资料作Meta分析。结果:符合纳入标准12项研究,累计1043例病例,Meta分析结果显示,体外冲击波组在视觉模拟评分(Visual Analogue Scale,VAS)评分、西安大略及麦克马斯特大学骨关节炎指标(The Western Ontario and McMaster Universities Osteoarthritis Index,WOMAC)评分方面均优于对照组。结论:体外冲击波疗法治疗膝关节骨关节炎患者的临床疗效较好,但由于纳入研究数量较少且诸多偏倚风险评价不明确,仍需高质量、大样本的随机对照研究加以佐证。

Objective:To systematically evaluate the validity and preponderance of extracorporeal shockwave therapy for knee osteoarthritis.Methods:Searched the database of CNKI,CBM,VIP,WanFang and Pubmed about the clinical randomized controlled trial of extracorporeal shockwave therapy for knee osteoarthritis before June 8,2021.The RCTs,about extracorporeal shockwave treatment of knee osteoarthritis in governor vessel was concealed,extracted and evaluated independently and objectively by two researchers.The extracted data were analyzed by Meta with Revman5.3 software.Results:12 studies met the inclusion criteria with 1043 cases.The results of Meta-analysis showed that VAS,WOMAC in the extracorporeal shockwave group were superior to those in the control group.Conclusion:extracorporeal shockwave has obvious clinical effect on patients with disturbance of knee osteoarthritis.However,due to the small number of included studies and unclear bias risk assessment,it still needs to be supported by high-quality,large-sample randomized controlled trials.