肾脏富血供肿瘤与乏血供肿瘤的CT血流动力学特征分析

CT Hemodynamic Characteristics of the High and Low Blood Supply Renal Tumors

目的 探讨肾脏富血供肿瘤与乏血供肿瘤在CT增强扫描动脉期的血流动力学特征有无差异。方法 回顾性纳入我院收治、有完整CT增强扫描和病理结果的单侧肾脏肿瘤患者76例,其中富血供肿瘤49例,乏血供肿瘤27例。计算所有患者在CT增强动脉期肿瘤侧肾动脉中段的血管壁压力、血管壁剪切力参数与对侧的比值,比较富血供组与乏血供组有无差异。结果 富血供肿瘤组的血管壁压力比值(1.07±0.09 vs 1.04±0.06;P=0.016)、管壁剪切力比值(1.12±0.13 vs 1.01±0.05;P<0.001)均高于乏血供肿瘤血,差异具有统计学意义。结论 肾脏富血供肿瘤侧肾动脉较大的血流动力学参数可能会促进肿瘤内微血管的形成,CT增强扫描动脉期血流动力学参数研究可以为临床提供更多的影像信息。

Objective To investigate the difference of hemodynamic characteristics between renal tumor with high blood supply and renal tumor with low blood supply during the arterial phase of CT enhanced scanning. Methods A total of 76 patients with unilateral renal tumors admitted to our hospital with complete CT enhanced scan and pathological results were retrospectively included,including 49 cases with rich blood supply tumors and 27 cases with poor blood supply tumors. The ratio of vessel wall pressure and the ratio of blood vessel wall shear stress between the tumor side and contralateral side were calculated for all patients,in the enhanced arterial phase of CT. And the differences between the rich blood supply group and the poor blood supply group were compared. Results The blood vessel wall pressure ratio of rich blood supply tumors(1.07±0.09 vs 1.04±0.06;P=0.016),wall shear stress ratio(1.12±0.13 vs 1.01±0.05;P<0.001) were higher than those of the tumor with poor blood supply,and the difference was statistically significant. Conclusion The large hemodynamic parameters of the renal artery on the side of the tumor with rich blood supply may promote the formation of microvessels in the tumor. The study of hemodynamic parameters in the arterial phase of CT enhanced scan can provide more imaging information for clinical practice.