百日咳鲍特菌的研究进展

Advances of Bordetella pertussis

百日咳鲍特菌是一种革兰氏阴性、短小的卵圆形球杆菌,该菌可通过飞沫传播,导致人们出现一系列呼吸道症状,称为“百日咳”疾病。近年来,百日咳的发病率在世界范围内呈上升趋势,学者们称之为“百日咳再现”。本文从微生物病原学、流行菌株的改变、病原学诊断、抗生素的应用及疫苗的研究进展几个方面进行综述。

Bordetella pertussis is a Gram-negative,short,oval coccus bacterium that spreads through droplets and causes people to experience a range of respiratory symptoms known as“whooping cough”.In recent years,the incidence of pertussis has been on the rise worldwide,which called“reemergence of pertussis”.This article reviews the latest research advances of Bordetella pertussis,including microbial etiology,circulating strains,etiological diagnosis,applications of antibiotics and vaccine progress,in order to draw attention to this microorganism.