基于“解毒化瘀、脾肾同治”理论辨治骨髓增生异常综合征经验

Experience of syndrome differentiation and treatment of myelodysplastic syndrome based on the theory of detoxification and removing blood stasis,simultaneous treatment of spleen and kidney

骨髓增生异常综合征(myelodysplastic syndromes,MDS)是一类造血干细胞恶性克隆性疾病,近年来,国内外对于MDS的治疗主要依靠表观遗传学治疗、化疗、干细胞移植,同时配合服用雷利度胺、阿扎胞苷和地西他滨等新药或补肾健脾类中药治疗。MDS的主要中医病因病机为瘀毒互结、脾肾亏虚,以解毒化瘀、脾肾同治为主要治疗原则,以解毒健脾、益肾养血类中药汤剂配合西药基础治疗,疗效颇佳。