摘要
目的观察华佗再造丸联合针刺辅助治疗老年脑卒中后偏瘫气虚血瘀证的临床疗效。方法将96例老年脑卒中后偏瘫气虚血瘀证患者采用随机数字表法分为对照组和治疗组,各48例。对照组给予西医常规对症治疗结合个性化康复训练,治疗组在对照组治疗方法的基础上给予华佗再造丸联合针刺治疗。治疗1个月后比较2组的临床疗效,以及治疗前后美国国立卫生研究院卒中量表(NIHSS)、Fugl-Meyer运动功能评估量表(FMA)、Barthel指数(BI)评分,血清神经元特异性烯醇化酶(NSE)、白细胞介素-10(IL-10)、同型半胱氨酸(Hcy)和氧化应激指标[超氧化物歧化酶(SOD)、丙二醛(MDA)]水平。结果治疗组总有效率为93.75%(45/48),对照组为66.67%(32/48),2组比较差异有统计学意义(P<0.01);治疗后2组NIHSS评分及血清NSE、IL-10、Hcy、MDA水平均明显降低,FMA、BI评分及血清SOD水平均明显升高,与同组治疗前比较差异有统计学意义(P<0.01),且治疗组对各项指标的改善作用更明显,与对照组治疗后比较差异均有统计学意义(P<0.01)。结论华佗再造丸联合针刺辅助治疗老年脑卒中后偏瘫气虚血瘀证疗效显著,可提高患者神经功能、运动功能及日常生活能力,改善血清学相关指标,值得临床推广应用。
Objective To observe the clinical efficacy of Huatuo Zaizao Wan(华佗再造丸)combined with acupuncture in the adjuvant treatment of hemiplegia after stroke with qi asthenia and blood stasis syndrome in the elderly.Methods 96 elderly patients of hemiplegia after stroke with qi asthenia and blood stasis syndrome were divided into a control group and a treatment group in a random number table,48 cases in each group.The control group was given conventional symptomatic treatment of Western medicine combined with personalized rehabilitation training,and the treatment group was given Huatuo Zaizao Wan combined with acupuncture therapy on the basis of the treatment method of the control group.After 1 month of treatment,the clinical efficacy of the two groups were compared,as well as the score of National Institutes of Health Stroke Scale(NIHSS),Fugl-Meyer Motor Function Assessment Scale(FMA),Barthel Index(BI),serum neuron-specific enolase(NSE),interleukin-10(IL-10),homocysteine(Hcy)and oxidative stress indices[superoxide dismutase(SOD),malondialdehyde(MDA)J before and after treatment.Results The total effective rate was 93.75%(45/48)in the treatment group and 66.67%(32/48)in the control group,and the difference between the two groups was statistically significant(P<0.01).After treatment,NIHSS score and serum levels of NSE,IL-1O,Hcy and MDA were significantly decreased,while FMA,BI score and serum SOD level were significantly increased in the 2 groups,and the difference was statistically significant compared with that before treatment(P<0.01).Meanwhile the treatment group had more obvious improvement on all indexes,and the difference was statistically significant(P<0.01)compared with that of the control group after treatment.Conclusion It has marked clinical efficacy,can effectively improve the the neurological function,motor function,daily living ability and serological related indicators of patients to use Huatuo Zaizao Wan combined with acupuncture in the adjuvant treatment of hemiplegia after stroke with qi asthenia and blood stasis syndrome in the elderly,which is worthy of clinical promotion and application.
作者
李胜春
LI Shengchun(Department of Geriatrics,Nanyang ZHANG Zhongjing Hospital,Nanyang,Henan,473000,China)
出处
《甘肃中医药大学学报》
2022年第6期70-74,共5页
Journal of Gansu University of Chinese Medicine
关键词
脑卒中
偏瘫
气虚血瘀证
老年
华佗再造丸
针刺
神经功能
运动功能
日常生活能力
血清学指标
临床疗效
stroke
hemiplegia
qi asthenia and blood stasis syndrome
the elderly
Huatuo Zaizao Wan(华佗再造丸)
acupuncture
neurological function
motor function
daily living ability
serological index
clinical efficacy