儿童尿路微生态群的研究方法及进展

Methods and progress on the urinary microbiome in children

正常人群泌尿系统中也存在常驻菌群,这些菌群的存在与人类的健康密切相关。泌尿系统微生态的变化与多种泌尿系统疾病的发生、发展及预后相关。该文综述了研究尿路微生态群的基本流程及泌尿系统疾病发生与尿路微生态群的相关性。着重探讨尿路微生态群与儿童反复泌尿系统感染关系的研究进展,为儿童反复泌尿系感染的诊疗提供新思路。

The urinary system of healthy people harbors residential urinary microbiota which closely related to human health.The changes of urinary micro-ecology are associated with the occurrence、development and prognosis of various urinary diseases.This review shows the basic procedure of studying the microbiome of the urinary system,and the correlation between the urinary diseases and the microbiome of the urinary tract.By focusing on the relationship between urinary microbiome and recurrent urinary tract infection in children,new ideas would be found for diagnosis and treatment of children’s recurrent urinary tract infection.